Medical Technical Officer - London, United Kingdom - Synnovis

Synnovis

Verified Company

London, United Kingdom

3 weeks ago

Posted by:

Tom O´Connor

beBee Recruiter

Description

The Synnovis Cancer Genetics laboratory at Guy's Hospital is part of the South East Genomics Laboratory Hub (SEGLH) and is the designated provider of adult solid tumour testing for the whole of the SEGLH geography.

Large scale expansion and transformation of the service is underway to ensure equity of access to the NHSE National Genomic Test Directory for Cancer.

A vacancy has arisen for an AfC band 6 equivalent medical technical officer (MTO3) who will be the lead laboratory technician for a subsection of the service, providing leadership, support and technical advice with respect to routine service delivery, equipment maintenance and procurement.

You will work closely with the technical team in a supervisory and trouble-shooting capacity and participate in the Duty Scientist rota.

Specialist knowledge and experience of a wide variety of molecular processes such as DNA/RNA extraction, quantification, quantitative real-time PCR and NGS library preparation, is essential to enable effective troubleshooting, supervision and training.

The Cancer Genetics team is comprised of around 50 administrative, scientific and technical staff within the cytogenetic and molecular genetic laboratories.

Testing is provided for patients with a wide range of adult solid tumours and haematological malignancies, in order to provide diagnostic and prognostic information and inform treatment decisions.

The service includes a substantial nationally and internationally renowned acute myeloid leukaemia (AML) mínimal residual disease (MRD) monitoring service which has close links with the King's College NIHR clinical trials AML MRD unit.

The laboratory is accredited according to UKAS 15189 standards and is an accredited training laboratory for the provision of the cancer genetic Scientific Training Programme (STP) and the Molecular Pathology of Acquired Disease Higher Specialist Training (HSST) programme.

Your development and learning

You will have a suite of learning opportunities available through The Synnovis Way Development programme, the Scientific Learning and Development Fund and the Synnovis Academy through which you can receive funding / support for advanced qualifications.

Technical Duties

Act as the lead technician for a sub-section of the Cancer Genetics Service, providing leadership and technical advice with respect to routine service delivery, equipment maintenance and procurement

Use laboratory information systems according to protocols

Undertake routine and complex sample preparation using accuracy and precision to correctly employ the procedures and protocols applicable to cancer genetics, including handling of patient information.

Laboratory duties include, but are not restricted to; setting up, harvesting, slide making and banding of liquid samples for G-banded and FISH analysis, de-paraffination of FFPE tissue sections for FISH, setting up and processing slides for FISH analysis, CD138+ selection of bone marrow samples using the Robosep machine, manual and/or robotic DNA and RNA extractions from a variety of human tissue types, preparing samples for molecular analysis using techniques such as Sanger sequencing, RT-PCR and Next Generation sequencing (NGS)

When appropriate accurately perform analysis of samples referred for Cancer Genetic analysis - this requires frequent and prolonged periods of concentration.

Analytical techniques used will depend on individual competencies and training; analysis will include but is not restricted to FISH analysis of bone marrow/peripheral blood samples and FFPE tissue sections, G-banded analysis, mutation analysis by Sanger sequencing, RT-PCR for AML MRD and NGS analysis of solid tumour samples

Undertake an appropriate proportion of the total workload of the Cancer Genetics section and take responsibility for accuracy of the work

Undertake accurate and precise data entry on the laboratory computer system, including drafting diagnostic reports under the supervision of senior staff

Provide cover for staff at the same or lower grade depending on the needs of the service

The post holder must communicate all problems and obtain help/advice from appropriate senior staff

Develop a close working relationship with the technical and scientific staff within Cancer Genetics and liaise with members of the other sections of the SEGLH as required

When necessary, prepare reagents and solutions used within the department

Liaise with the clinical scientists regarding technical matters, sample preparation and selection of further tests as required

Perform automated, semi-automated and manual processing of specimens which may require a high level of dexterity.

Prepare, process and analyse samples for clinical trials and research and development projects as and when required

Perform quality control measures to monitor analytical performance, take corrective action where applicable and report any failures to an appropriate member of staff

Set up equipment for use by other membe