Postdoctoral Researcher in Cellular Therapeutics - Oxford, United Kingdom - University of Oxford
Description
Contract type:
Fixed-term contract until 30th June 2026**
Hours: Full-time
About the role
We are looking for a postdoctoral researcher to work in Translational Research Immunology Group (TRIG) on translational, collaborative project funded by EU.
You will be placed in the Institute of Developmental and Regenerative Medicine on the Old Road Campus working in a close collaboration with the Oxford Kidney Pathology group.
You will be part of a bigger EU-funded project which goal is to develop a safe and efficient cell therapy based on genome edited T cells for IgA nephropathy (IgAN).
IgAN is the most common glomerulonephritis; IgA-rich complexes are deposited in renal glomeruli, leading to renal failure a third of cases, but there are currently no effective treatments, so this an area of significant unmet need.
Redirected T cells offer the potential to specifically target pathogenic IgA1 producing cells.
You will work closely with members of TRIG and Oxford Kidney Pathology groups, including students, other post-docs and research assistants as well as international collaborators within the EU consortium.
You will be responsible for testing T cell therapeutics developed by our consortium, using in vivo models of glomerular immune complex disease as well as the establishment of a novel model for IgA Nephropathy.
Additionally, you will contribute to spatial transcriptomics and proteomics in human IgAN kidney samples.About you
This full-time post is available immediately and is fixed-term until June 2026 in the first instance.
Application Process
Interviews will be held on Friday 24 May 2024.
**Committed to equality and valuing diversity
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