Clinical Research Associate - Newcastle upon Tyne, United Kingdom - Newcastle University

Tom O´Connor

Posted by:

Tom O´Connor

beBee Recruiter


Description

Salary:
£34,770 to £57,570 per annum

Newcastle University is a great place to work, with excellent benefits.

We have a generous holiday package; plus the opportunity to buy more, great pension schemes and a number of health and wellbeing initiatives to support you.


Closing Date: 31 January 2024

The Role


This post is linked to The NIHR Newcastle Biomedical Research Centre (BRC) Dementia, Mental Health and Neurodegeneration Theme, the Lewybodylab and part of the Mental Health, Dementia and Neurodegeneration Research Theme in the Translational and Clinical Research Institute at Newcastle University.


The post will provide funding to complete either a PhD or MD undertaking research that helps deliver the dementia theme objectives of the Newcastle BRC.

The focus of this post will be to develop a non-invasive biomarker based on specific electroencephalographic (EEG) spatio-temporal feature motifs which strongly associate with cholinergic function and which is fit for purpose in early/ prodromal Lewy body dementia.

It would also be expected that the post-holder would also contribute to other ongoing clinical trial studies within the research group, including a study investigating a novel treatment for Parkinson's disease (Obeticholic acid for the Amelioration of Cognitive Symptoms trial - 3; OACS-3).


You will join a vibrant research group of international standing and join a cadre of clinical and non-clinical post-graduate students in the wider Institute and Faculty at the University.

You will be responsible for formulating a research plan, developing collaborations internally and externally to develop your skills and prosecute the research, in conjunction with your PhD/MD supervisory team.

You will develop the methodology, techniques, equipment and analysis techniques necessary for the work; consent and screen participants; and undertake the research activities.

You will write up your findings for presentation at international conferences, publication in peer reviewed journals and your thesis.

Key Accountabilities

  • Register for a PhD / MD and meet the ongoing requirements for postgraduate research at Newcastle University.
  • Contribution to the research programme of the Translational and Clinical Research Institute and the Newcastle BRC under the clear guidance of a member of an academic staff or Principal Investigator.
  • Assist in the identification, screening, recruitment and assessment of Parkinson's disease patients with mild cognitive impairment and patients with prodromal / early dementia with Lewy bodies from local movement disorders and memory clinics.
  • Be responsible for clinical assessments of patients, including history taking, physical examination and diagnostic confirmation.
  • Perform bloods as part of the studies and other clinical tests including, for example, electrocardiograms.
  • Have responsibility for prescribing medications appropriate to the study and responsible for addressing any issues with side effects or adverse events.
  • Be responsible for delivery of the neurophysiological component of the study including transcranial magnetic stimulation and electroencephalography protocols.
  • Interact with other members of the CREED and OACS3 team, including for example, Principal investigator, other coprincipal investigators, members of gait team, clinical ageing research unit staff members, pharmacy, associated research assistant/associates, laboratory technicians and postdoctoral scientists.
  • Interact with your supervisors, biostatisticians and bioinformaticians to discuss the data derived from your samples and devise appropriate plans for analysis.
  • Help to prepare data for publication in relevant, high impact factor journals.
  • Provide guidance to other staff and students, potentially including supervision of undergraduate research project students.
  • Attend and present work at laboratory, Biomedical Research Centre and national/international meetings.
  • Be prepared to contribute to events celebrating the public engagement of science/social sciences/humanities.
  • Coordinate own work with that of others, deal with problems that may affect the achievement of research objectives and contribute to the planning of the project.
  • Work to deadlines and manage, with support, competing priorities.
  • Ensure that personal knowledge and training in relevant fields of study is kept up to date, closely managed by a senior academic or Principal Investigator.
  • Work with other researchers in a team and actively participate in collaborative research.
  • May be involved in the recruitment and delivery of other related clinical trials.
  • Undertake agreed and limited clinical activities in Cumbria, Northumberland, Tyne and Wear NHS FT in the context of supporting study activities and recruitment.
The Person

Knowledge, Skills and Experience

  • Expert knowledge of dementia and its causes.
  • Excellent Database Management and record keeping.
  • Excellent clinical skills with experience in th

More jobs from Newcastle University