Staff Scientist - Cambridge, United Kingdom - Wellcome Sanger Institute

Tom O´Connor

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Tom O´Connor

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Description

Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity's greatest challenges.


The Doyle Group at the Wellcome Sanger Institute is seeking a collaborative and ambitious
Staff Scientist to lead the generation and analysis of large-scale genomic datasets for soil-transmitted helminths.


About the role:


Your role will be to lead the development of new genomic approaches to understand the genetic diversity of soil-transmitted helminths, a group of parasitic worm species that collectively infect over 1.5 billion people worldwide.

Facilitated by collaborations with the STOP Consortium ) and recent EDCTP funding ), you will generate large-scale genomic datasets that will be used to identify genetic variation associated with poor response to drug treatment, population structure and composition between and within parasite species across multiple sites in Africa, and their interaction with the host microbiome.

We anticipate this work will lead to fundamental new insights into the biology and genetics of soil-transmitted helminths and factors that influence response to drug treatment.


About you:


We are looking for an enthusiastic and ambitious individual to develop, drive and deliver cutting-edge research focused primarily on genome-wide analyses of genetic diversity in soil-transmitted helminth populations.

You will be proficient in both molecular biology and computational biology. You will be detail orientated, analyse data and interpret results in their biological context, and prepare manuscripts for publication.

You will be able to work independently, have excellent interpersonal and communication skills, and interact well with collaborators and colleagues and the broader scientific community.


About us:


The Doyle group is focused on investigating the phenotypic and genotypic diversity of parasitic worms and the mechanisms that shape parasite populations over time.

To do so, the group employs a range of molecular and computational techniques, from de novo assembly and population genetics to single-cell genomics approaches, to understand how helminth populations evolve at both macro- and micro-evolutionary time scales.

The group works on a range of human- and animal-infective helminth species, with a particular focus on the sheep gastrointestinal parasite Haemonchus contortus and soil-transmitted helminths.

Our research is supported by a strong collaborative network that the Staff Scientist will benefit from both inside and outside of the Sanger Institute.

To learn more about us and our work please visit our team website.


Essential technical skills:


  • PhD in helminth biology and subsequent experience in soiltransmitted helminth research
  • Proficiency in handling soiltransmitted helminths and related samples
  • Experience with molecular biology techniques including RNA/DNA extraction, qPCR
  • Experience in working with bioinformatic tools relevant to mapping, variant calling, and analysis of genomic data from helminths
  • Familiarity with the Nagoya Protocols, and other legislation relevant to the use of biological samples, DNA, and tissue in research
  • Experience in writing scientific publications

Competencies and Behaviours:


  • Ability to work effectively, both independently and within a team, contributing to discussions and disseminating knowledge and information
  • Strong interpersonal skills with the ability to negotiate and build lasting relationships.
  • Resilient and selfmotivated to take learnings from unsuccessful experiments.
  • Meticulous attention to detail.
  • Excellent organisational and communication skills.
  • Good problemsolving skills.
  • Experienced in planning experiments and research, and in setting strategic goals.

Application Process:


Salary range:
£43,583 to £52,300 (dependent on skills and experience)


Contract Type:
Fixed-term for 2 years in the first instance, beginning January 2024


Closing Date:13th August 2023


Working at Wellcome Sanger:

Our flexible-hybrid working environment is designed to support a healthy work-life balance.

This means you can work flexibly with a combination of working from home, and working from our Campus to allow you to focus on being productive and part of the team while enjoying the benefits of working flexibly.


We aim to attract, recruit, retain and develop talent from the widest possible talent pool, thereby gaining insight and access to different markets to generate a greater impact on the world.

We have a supportive culture with the following staff networks, LGBTQ+, Parents and Carers and Race Equity to bring people together to share experiences, offer specific support and development opportunities and raise awareness.

The networks are also a place for allies to provide support to others.


We want our people to be whoever they want to be because we believe people who bring their best selves to work, do their best work.

That's why we're committed to creating a truly inclusive culture at Sanger Institute.

We will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.


Our Benefits:

We are proud to deliver an awarding campus-wide employee wellbeing strategy and programme.

The importance of good health and adopting a healthier lifestyle and the commitment to reduce work-related stress is strongly acknowledged and recognised at Sanger Institute.


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