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About Jessica Bates:
I am a final year PhD student at Nottingham Trent University researching the effect of ageing on the blood-brain barrier. This incorporates in vivo studies with male and female mice up to the age of 22 months, whereby I have completed I.V., I.P, S.C routes of administration as well as surgical anaesthesia monitoring. I have also worked as a research technician within academia for 2 years working with in vitro and in vivo research streams and a 3 month placement in industry. I am passionate about science and wish to continue in my career in this field.
Experience
Nottingham Trent University: Laboratory demonstrator (Bioscience department), 2021-present
- Assist in demonstrating and teaching students at undergraduate and master’s level in multiple disciplines.
- Planned and supervised undergraduate and Masters’ level research projects (2022-2024)
University of Nottingham: Research Technician (Breast Cancer Pathology Research Group), 2019-2020
- Assisted with the collection of tissue blocks and slides and maintained accurate data storage records in
compliance with the human tissue act (HTA).
- Sectioned FFPE and Tissue MicroArray tissue blocks whilst maintaining accurate records of tissue use.
- Performed immunohistochemistry and routine H&E including validation and quality control.
- Produced and adhered to SOP, CoSHH and Risk Assessment documents
- Produced and implemented project workflow plans for various aspects of project
- Assisted PhD students in laboratory techniques, theoretical knowledge and ordering of consumables
University of Sheffield: Trainee Research Technician, (Sheffield Institute for Translational Neuroscience, 2016-2017
- Worked with a vast range of techniques such as Tissue Culture of human cells, Histopathology, Histology, Cell culture, Microarrays, DNA extraction from blood, drug discovery panels
- Informally demonstrated and troubleshoot laboratory techniques to MSc and work experience students
- A part of a team with responsibilities affecting projects in the entire department
- Beginner and Intermediate immunohistochemistry courses
University of Sheffield: Auditor of Tissue, October 2018-March 2019
- Audited both FFPE and frozen tissue at the Sheffield Tissue Brain Bank
- Collated data into an online database and amending any abnormalities in accordance with HTA
Education
PhD project: Nottingham Trent University, University of Nottingham (September 2020-)
- ‘The Role of the Neurovascular Unit in Maintaining Normal Blood-Brain Barrier in ageing’
- Techniques applied: Immunohistochemistry, Confocal and thunder microscopy, lipid nanoparticle production,
- In vivo animal work: Rodent animal licence (PIL A/B/C obtained June 2021), Behavioural studies, dosing (I.V. and I.P), cardiac perfusion, anaesthesia monitoring of MCAo surgical studies, cardiac perfusion, in vivo imaging including IVIS and MRI
- Liposome characterisation: TEM, DLS, fluorescence intensity
- Analysis software: GraphPad Prism, Image J
MSc Translational Neuropathology, University of Sheffield, 2019 (Distinction)
BSc (Hons) Biochemistry, Sheffield Hallam University, 2014-2019 (1st Class)
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