Patrick Amodubello

I am a Cancer Biology masters graduate that is passionate about science and I have experience in many laboratory settings

Associate scientist (Bi-specific antibody discovery), 10/2022-present

Sanofi (Kymab), Cambridge, UK

• Support an antibody discovery project to identify bi-specific or tri-specific antibodies for drug discovery to Development Candidate stage
• Participate in the formulation of bi-specific or tri-specific discovery activities including MOA, target validation, functional screening to assess molecule efficacy
• Develop and perform binding and cell-based functional assays for screening and functional assessment of antibodies
• Analyze and interpret experimental data and trouble-shooting technical issues
• Maintain accurate and up-to-date records of research 

Research associate (Protein), 04/2022 – 10/2022

Nuclera Nucleics, Cambridge, UK

• Cell free protein synthesis 
• Protein quantification via Bradford assays, fluorescence (microplate reader), biodrop etc.
• Production of DNA constructs (manipulation by adding flanks)
• DNA purification via kits and other methods
• Protein purification with magnetic beads 
• DNA agarose gels, SDS Page, western blotting
• Various protein membrane staining, i.e., ponceau, Coomassie, histidine etc.
• Report and SOP writing
• Experiment troubleshooting

BSc Natural Sciences, 05/2020 

Trinity College Dublin – Dublin, Ireland

MSc Cancer Biology and Therapeutics, 07/2021 

University of Kent – Kent, UK

Modules:

• Practical and applied research skills for advanced biologists
• The molecular and cellular basis of cancer
• Genomic stability and cancer
• Cancer research in focus
• Cancer therapeutics: from the laboratory to the clinic