Research Assistant - Belfast, United Kingdom - Queen's University Belfast
Description
Job details:
Job reference
23/111064
Date posted
03/07/2023
Application closing date
24/07/2023
Salary
£30,619 per annum
Job category/type
Research
Attachments
- Blank
Research Assistant:
Job description- The postholder will join the inflammasome biology research team led by Dr Rebecca Coll in the Wellcome-Wolfson Institute for Experimental Medicine. We study the fundamental biology of inflammasome signalling pathways to inform the development of novel treatments for inflammatory diseases.- This short-term position will be focused on examining the function of CARD16 in human myeloid cells. It will involve the culture of human induced pluripotent stem cell (hiPSC) macrophages and primary macrophages, activation of inflammasomes and other innate immune receptors, and a variety of assays to assess cell signalling.- This position is suited to an ambitious, productive, and collaborative individual.- A Degree in immunology, biochemistry, cell biology, molecular biology, or a relevant biomedical science.
- Significant handson experience in the following:
- Culture of human iPSC-derived macrophages and iPSC-derived microglia.
- Flow cytometry for macrophage characterisation.
- Isolation and culture of primary human macrophages and use of siRNA in these cells.
- Assays for measuring innate immune signalling pathways including Western blotting, ELISAs, cell death assays, and ASC speck formation assays.
- qRT
- PCR for gene expression.
- At Queen's our people are at the heart of everything we do. As a staff member you will become part of a vibrant organisational culture, which will provide you with the opportunity to achieve your full potential and enhance your career through a continuous focus on learning and development.
We offer an excellent employment package that includes:
- Great terms & conditions
- Pension schemes
- Flexible working by enabling you to design your working week in collaboration with your manager through a blend of remote and office working
- Familyfriendly initiatives
- Career development opportunities
- Support for health & mental wellbeing
- Generous holiday entitlement of 8.4 weeks a year (made up of 23 days annual leave, 10 closure days and 9 bank holidays)
We have created an inclusive culture by establishing staff networks such as iRise (Black, Asian, Minority Ethnic and International Staff Network) and PRISM (LGBTQ+) which help us progress equality.
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