Research Associate in Cancer Biology and - Manchester, United Kingdom - The University of Manchester

The University of Manchester

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Manchester, United Kingdom

1 week ago

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Tom O´Connor

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Description

The University of Manchester

The University of Manchester is the largest single-site university in the UK with around 38,000 students and more than 11,000 staff.

We aim to become one of the top 25 research universities in the world by 2020 and are committed to delivering an outstanding teaching and learning experience; contributing to the social and economic success of local, national and international communities; producing the highest calibre graduates; and developing our staff to be amongst the very best of their peers.

To achieve our ambitious goals we aim to attract and retain the very best people to work across a range of academic disciplines and support functions

The Faculty of Biology, Medicine and Health (FBMH)

Our strategic partnerships
The new Faculty has a number of key strategic partnerships that underpin its ambitions to develop ground-breaking research.

Working alongside six local NHS Trusts, the Faculty is a key member of the Manchester Academic Health Science Centre (MAHSC) - a federation of equal partners that unites leading healthcare providers with world-class academics and researchers.

It aims to be a global centre for the delivery of applied health research and education and provide leadership for our local and regional health systems.

It also plays a leading role in Health Innovation Manchester (HInM), which was launched in September 2015, as part of the UK Government's decision to devolve health and social care responsibilities to Greater Manchester.

HInM offers a unique opportunity to bring together health and social care, academic and life science related business resources across the region to deliver an innovative health ecosystem that can help accelerate innovation into our local health and social care systems, enhance our global scientific standing and act as a magnet for inward investment.

Key partnerships in the charitable sector include Cancer Research UK; Diabetes UK; and the Wellcome Trust; and the Faculty has research and funding links to a number of commercial organisations including Unilever, AstraZeneca, GlaxoSmithKline and Boots, who will help us to bring new drugs and products to the market.

Working for the University of Manchester

The University of Manchester strives to make our community a welcoming, caring and enthusiastic one, fuelling ambition with opportunities and support to help us all achieve our personal and professional goals.

Our diverse job opportunities include an attractive benefits package with family-friendly policies that provide for flexible working.

We care deeply about career and personal development, offering a structured induction programme for new staff, an annual performance and development review, staff training for all career stages and mentoring opportunities to support your career development.

We have a genuine commitment to equality of opportunity for our staff and students, and are proud to employ a workforce that reflects the diverse community we serve.

As a global institution, situated at the heart of a lively, culturally diverse city, we welcome applicants of all nationalities.

To help international job applicants plan for life in the UK, we have put together some useful information on passports and visas, travel to the UK, accommodation and a number of other practical considerations.

The Division of Pharmacy & Optometry
The Division of Pharmacy and Optometry (DPO) is dedicated to research across all parts of our discipline areas.

Our Pharmacy research focuses on medicines, aiming to improve aspects of their design, development and use, as well as research covering the practice of pharmacy and the delivery of pharmaceutical services to patients and consumers.

This is being advanced within a number of strategic research themes which encompass both the science and practice of pharmacy.

Optometry research is also broadly based, covering fundamental aspects of vision science, corneal health, contact lenses and the ocular surface, low vision and the accommodation system.

Research within the DPO is funded by the Research Councils, Charities, EU, DoH/NIHR and Industry including the establishment of the AstraZeneca-funded (£1.5m) North West Centre for Advanced Drug Delivery.

DPO is the home of the Centre for Applied Pharmacokinetic Research and Eurolens Research.

Project Background / Overall Purpose of the Post:Ewing sarcoma is highly aggressive and the second most frequent bone tumour of childhood and adolescence. Treatment comprises local surgery, radiotherapy (RT) and chemotherapy, which are associated with acute and chronic adverse effects. Whilst a survival rate of up to 80% is observed in patients with standard-risk and localised disease, outcome is dismal for patients presenting with metastatic disease, or whose tumours are refractory to initial chemotherapy.

Ewing sarcomas are immunologically "cold", having an immune-suppressive tumour microenvironment. Therefore, augmenting HLA-A,B,C