Senior Bioinformatician - London, United Kingdom - Engitix
Description
Your mission:
- Partner with Engitix scientists and external collaborators to help design experiments, draft and implement analysis plans, and iteratively deliver actionable biological insights and visualizations
- Refine key questions, clearly articulate concepts, needs, and potential solutions, and effectively communicate results to diverse teams
- Establish, test, and improve analysis pipelines, especially for proteomics data
- Identify, ingest, validate, and harmonize key data resources to expand upon and translate insights broadly across modalities, models, and cohorts
- Develop innovative analytical approaches and analysis plans integrating, analyzing, and interpreting highdimensional multimodal datasets to provide evidence to progress the Engitix portfolio
- Ensure data and analytics integrity through best practices in FAIR data, reproducibility, and documentation
Your profile:
As well as strong communication, organizational, and time management skills, you will have:
- Ph.
- Strong programming/scripting skills in R and/or Python, as well as experience working with cloud services (e.g., AWS), containerization, workflow languages (e.g., NextFlow), and SQL databases
- Deep expertise in quantitative proteomics, including familiarity with mass spectrometry technologies, TMT labelling, and targeted proteomics as well as handson experience in analysis and key public data resources.
- Strong handson experience of performing analyses in at least one of:
- Bulk and/or scRNAseq
- Molecular imaging, including spatial proteomics and/or transcriptomics
- Multiomics and data integration
- Target and/or Biomarker discovery and validation
- Strong foundation in statistics and/or machine learning, including experience with methods such as survival analysis, regression analysis, dimensionality reduction, classification, and clustering
- Desirable: Experience working in a crossfunctional team in Oncology or Fibrosis
Why us?:
- Be part of a motivated, dynamic team supporting cutting edge drug discovery
- Constant opportunities to learn, grow, and explore the many opportunities for data science to have impact on drug discovery and development
- State of the art offices at The Westworks, White City London
- Competitive reward package including private medical insurance, bonus, pension, and much more
About us:
We are pioneering the way to significantly improve the lives of fibrosis and solid tumour patients and their families.
Through our unique understanding of the extra-cellular matrix (ECM), and our world-class technology and approach, we are unlocking insights and enabling the generation of new, advanced therapeutics.
At Engitix, relationships are the foundation of accomplishment.
We are one team working together in service of our mission to significantly improve the lives of fibrosis and solid tumour patients and their families.
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