Senior Scientist - Slough, United Kingdom - Hyper Recruitment Solutions Ltd

Hyper Recruitment Solutions Ltd
Hyper Recruitment Solutions Ltd
Verified Company
Slough, United Kingdom

2 weeks ago

Tom O´Connor

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Tom O´Connor

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Description

We are currently looking for a Senior Scientist - Bioinformatics to join a leading pharmaceutical company based in the Slough, Berkshire area.

As the Senior Scientist - Bioinformatics you will be responsible for linking target mechanisms to human diseasepathobiology.

KEY DUTIES AND RESPONSIBILITIES:
Your duties as the Senior Scientist - Bioinformatics will be varied however the key duties and responsibilities are as follows:

  • To analyse bulk and single cell RNA-seq from patient samples and combine with gene expression from in vitro and ex vivo perturbations of model systems to link target mechanisms to human disease pathobiology.
  • Working as part of a multi disciplinary team to improve our understanding of the molecular mechanisms that drive complex, chronic diseases and response to treatment.
  • Generate unique insights regarding molecular evidence of efficacy; refined understanding of MoA; and identification of patient molecular endophenotypes.

ROLE REQUIREMENTS:

  • Relevant degree (MSc) in biology/ bioinformatics or computer science
  • Proven industry experience withimplementing and executing NGS pre-processing and analysis pipelines preferably in a parallelised cloud environment i.e. DNA Nexus
  • A working knowledge and practical experience with RNAseq analysis best practices and ability to leverage a diverse toolbox of methods for biological interpretation of gene expression data including, pathway analysis, functional module detection, and causalreasoning will be an advantage.

Key Words:
NGS / RNAseq / R / Python / Unix / Linux / DNA Nexus / Biology / Bioinformatics
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