Mathematical Modeller - Oxford, United Kingdom - University of Oxford

University of Oxford

Verified Company

Oxford, United Kingdom

1 week ago

Posted by:

Tom O´Connor

beBee Recruiter

Description

A highly motivated, ambitious Mathematical Modeller is required to develop and analyse mathematical models that focus on the role of sortilin-mediated progranulin-related pathways in neurodegenerative diseases, reporting to the Oxford-GSK IMCM co-director Professor John Todd and Dr Anna Sher, Director in Quantitative Systems Pharmacology at GSK, and with oversight from the Oxford-GSK IMCM Programme Manager.

It is essential that you hold a relevant PhD/DPhil in Applied Mathematics, Mathematical Biology, Engineering, Physics, Computational Biology, Pharmaceutical Sciences, or other related discipline.

You will have training or previous experience in building differential equation-based models of physiological pathways or biological systems, quantitative systems pharmacology (QSP), quantitative systems toxicology (QST), semi-mechanistic pharmacodynamic (PD) or physiologically-based pharmacodynamic (PBPK) models.

You will also have an understanding of principles and statistical aspects of mathematical modeling and simulation, including sensitivity analysis and parameter estimation techniques.

Finally you will have interest in learning new areas of biology, building novel quantitative and computational skills and sharing learnings as well as excellent written and verbal communication skills, including the ability to communicate technical concepts to non-technical audiences.

This position is offered full time on a fixed term contract until 30 September 2027 and is funded by the GSK.