Research Fellow - Coventry, United Kingdom - University of Warwick

University of Warwick

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Coventry, United Kingdom

2 weeks ago

Posted by:

Tom O´Connor

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Description

Location
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***University of Warwick Campus, Coventry

Department
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***Warwick Medical School - Warwick Clinical Trials Unit

Position Type
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***Full Time, Fixed Term

Duration
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***Fixed-term for three years

Salary
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***£33,966 - £44,263 per annum

Additional Payments
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***Plus a non pensionable market supplement of £5,000 per annum.

About the Role
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***Warwick Medical School (WMS) at the University of Warwick wishes to appoint a Research Fellow to develop statistical methods for analysing adaptive platform trials.

The exciting project is funded by MRC-NIHR Better Methods for Better Research Programme for 3 years.

Salary will be within the range £33,966 - £44,263 per annum, depending on qualifications and experience, plus a market supplement of £5,000 per annum.

You will develop methods to analyse adaptative platform trials whilst addressing statistical challenges the analysis pose.

Platform trials are multi-arm, that is, multiple experimental treatments are tested, and are multi-stage, that is, multiple interim analyses are performed to adapt the trial based on accrued evidence.

Therefore, there is a challenge to adjust analysis for multiplicity arising from multiple treatments and multiple interim analyses. New experimental treatments may also be added partway through a platform trial.

This poses additional challenge of whether, whilst comparing an added treatment to the control treatment, patients randomised to the control treatment before adding the treatment should be included, and if so, how.

Other challenges include the fact that the standard of care and hence control treatment may change during the trial. Analytic and simulations techniques will be used.

You will work with Principal Investigator Dr Peter Kimani based in Warwick Clinical Trials Unit (WCTU) in WMS, Prof Nigel Stallard, Professor of Medical statistics and Director of WCTU, Prof Keith Abrams, Professor of Statistics & Data Science in the Department of Statistics in the University of Warwick, Prof Andrew Metcalfe, an orthopaedic surgeon and a Professor of Clinical Trials in WCTU and Prof Jeremy Chataway, a consultant neurologist and Co-Programme Lead for Neurodegenerative Diseases at the UCL MRC Trials Unit.

The post is primarily research, but there will be opportunities for teaching and assisting in the supervision of postgraduate students.

About You
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***If you are near submission or have recently submitted your PhD but have not yet had it conferred, any offers of employment will be made as Research Assistant at the top of level 5 of the University grade structure. Upon receipt of evidence of the successful award of your PhD, you will be promoted to Research Fellow on the first point of level 6 of the University grade structure.

About the Department
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***Based within Warwick Clinical Trials Unit (WCTU), you will be appointed at Warwick Medical School (WMS) at the University of Warwick. WCTU has a strong track record in delivering excellent research that inform clinical practice. Around 20 statisticians provide design and analysis expertise to WCTU's large portfolio of studies, mostly multicentre clinical trials. WCTU statisticians collaborate widely with other groups in WMS, the wider university such as the internationally renowned department of statistics and the local NHS Trust. Also, based on WCTU trials and individual research interests, they conduct applied statistical methodology research, with multiple ongoing projects funded by MRC-NIHR Better Methods for Better Research Programme. WCTU statisticians support teaching in WMS, from undergraduate to supervising PhD students undertaking statistical methodology research. There are regular meetings and seminars that cover both applied and methodology research.

For further information about Warwick Medical School, please visit our website.

About the University
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***Born in the 60s with a mindset of boldness, imagination and collaboration, the University of Warwick is a world-leading research-intensive university with the highest academic and research standards. We're one of the world's top universities, ranked 67th in the world and 10th in the UK*, with 92% of our research assessed to be 'world leading or internationally excellent'**.

You'll be joining a diverse, innovative and globally connected community committed to igniting real world progress.

Here at Warwick, we offer you opportunities to follow your ambitions as long as you bring the energy and determination to succeed.

QS World University Rankings 2024

**Research Excellence Framework 2021

How to Apply
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***The interviews will be held on a date to be confirmed.

What we Offer
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***We will provide you with a great range of benefits, which include an attractive pension scheme, 30 days holiday plus Christmas clo