Research Fellow - St. Andrews, United Kingdom - University of St Andrews
Description
Applications are sought for a committed Research Fellow to work with Dr Paolo Annibale, at the School of Physics and Astronomy, conducting research for a Leverhulme Trust funded project entitled _Bottom up nanoscale control of compartmentalized cellular signaling: geometry and finesse.
The primary duties will be to support the team working on fundamental biophysics and cell biology questions using innovative fluorescence microscopy and spectroscopy approaches.
The focus of the project will be to establish an optomechanical platform to control the local geometry of living cells, in order to observe in a controlled environment the effect of modulating geometry on key signalling cascades used by human cells to respond to extracellular stimuli.
To this purpose, we will employ advanced fluorescence microscopy approaches, including super-resolution imaging, fluorescence resonance energy transfer and fluorescence correlation spectroscopy.
The successful applicant will be expected to lead the optics and microscopy axis of the project, establishing a custom-made confocal microscope, and allowing its combination to force spectroscopy tools such as optical tweezers or an Atomic Force Microscope.
The successful applicant will have to interface with a highly interdisciplinary team, and will have the opportunity (and challenge) of becoming familiar with methods outwit the strict remit of the physical sciences.
The successful applicant will have (or be near to completion of) a PhD in Physics/Engineering/Biomedical Engineering with expertise in construction of advanced optical systems and instrument control by software (such as Python or National Instruments Labview).
Ability to work successfully in a small team, supervising postgraduate students and willingness to learn new methods will be amongst key characteristics sought in the successful applicant.
The post is available for 24 months starting 1st May 23 or as soon as possible thereafter, with the possibility of extension upon satisfactory performance, for up to a total of 54 months.
Applications are particularly welcome from women, people from the Black, Asian and Minority Ethnic (BAME) community, and other protected characteristics who are under-represented in research posts at the University.
Interviews will be held on 15 March 2023
Please quote ref:
AR2779MR
Closing Date: 28 February 2023
Further Particulars:
AR2779MR **School of Physics & Astronomy
Salary:
£35,333 - £38,592 per annum
Fixed Term: 24 months
Start: 1 May 2023 or as soon as possible thereafter
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