Bioinformatician - Newcastle upon Tyne, United Kingdom - QuantuMDx Group Ltd

Description

Overview:

Responsibilities:

• Utilize data analysis skills to interpret biological data
• Implement machine learning algorithms for predictive modeling
• Collaborate with researchers to develop AI solutions for genomic analysis
• Conduct data mining and statistical analyses
• Develop and maintain bioinformatics pipelines
• Utilize cloud computing platforms such as AWS for largescale data processing

Experience:


Required Skills:

• Proficiency in Python for data analysis
• Experience with C++ for algorithm development
• Knowledge of machine learning techniques
• Familiarity with deep learning frameworks
• Experience with cloud computing technologies, particularly AWS

Nice-to-Have Skills:

• Background in bioinformatics or related field
• Familiarity with data mining techniques
• Knowledge of R programming language

Join us in our mission to advance bioinformatics, research & development and make a meaningful impact on the field.


Full Job Description below
Bioinformatician

About the job


Position overview:

Based at Lugano Building, Newcastle upon Tyne. This role reports to the Early Phase Assay Development Team Lead.

Key Roles & Responsibilities

Performing a combination, but not necessarily all, of the following duties:

This role requires a Bioinformatician to support the VP R&D in general tasks such as; software development, database maintenance and report generation.

Work with the QuantuMDx Group commercialisation program by working within the Assay Team to design assays for the Company's diagnostic platform, the Q-POC.

A key success factor for this position is the ability to work in a fast paced, cross functional group environment, with a willingness to be involved across a wide area of responsibilities.

A great capacity and desire for taking on new responsibilities and challenges is essential as the company grows and projects expand.

The jobholder will be expected to:

• Work within the Assay Team to deliver molecular diagnostic product pipeline.
• Attend regular lab meetings.
• Identify appropriate reference sources for sequences, for example public sources such as GISAID and NCBI databases.
• Be familiar with NextGen sequencing and associated pipelines.
• Collate and annotate reference sequences across multiple microorganisms.
• Generate, record, manipulate, analyse and present complex data to line manager, colleagues, senior management and external partners.
• Assist in report writing and generation of SOP's.
• Maintain records, logs and or databases of analyses for regulatory reporting purposes.
• Undertake _in silico_ inclusivity and exclusivity testing and analyse homology to confirm target suitability.
• Undertake periodic _in silico_ review of existing assay designs to confirm ongoing suitability of the assay for VOC, VUI and variants being monitored.
• Work on collaborative projects with external partners and be point of contact for bioinformatics.
• Keep up to date with the literature on point of care diagnostics, assay design, infectious disease diagnostics and other relevant areas.
• Work within the quality systems following GDP and ISO 13485 standards.

Experience, knowledge and requirements

• Relevant experience in bioinformatics with a strong knowledge of microbial genomics.
• Familiarity with sequencing data (Sanger and NGS) and standard bioinformatics tools (alignment, variant calling, assembly etc.)
• Experience in data manipulation and analysis of large genomic datasets.
• Knowledge and competence in Python, Docker, Git, Linux, MySQL or similar software development tool.
• Knowledge of nucleic acid amplification and detection chemistries.
• Knowledge of statistics.
• Ability to work to the Quality Management Systems in line with ISO13485 standards.
• Excellent work ethic and strong communication skills.
• Ability to work in a changing environment on complex projects.
• Previous experience in the design and development of diagnostic devices
• Demonstrated ability to lead collaborative projects with external partners.
• Previous experience in an industry or startup setting.
• Previous experience in the validation and verification of molecular diagnostic assays
• Hands on experience with the manipulation and development of PCR chemistries for diagnostic tests.
• Knowledge of infectious diseases and their diagnosis.
• GPU programming.

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Be eligible to work full time in the UK without restriction.

Company Overview
QuantuMDx is a progressive MedTech company passionate about point of need molecular diagnostics.

Our mission is to make transformative, quality diagnostic technologies accessible to everyone, so that diseases can be detected and treated earlier.

The Q-POC is a simple to use, portable, sample-to-answer multiplex PCR device. It has been designed for use in a range of settings, such as hospitals, clinics, pharmacies, workplaces and in the field, providing laboratory equivalent PCR results directly to the healthcare provider at the point-o