Senior Molecular Biologist - Morecambe, United Kingdom - Advanced Bacterial Sciences Limited

Description

JOB DESCRIPTION

Job Title:
Senior Molecular Biologist


Application requirement:
Cover Letter and CV


Company:
ABS - Advanced Bacterial Sciences


Department:
Science & Innovation


Address:
Lancaster/Morecambe - England


Reporting to:
Dr Gabriela Meirelles


Duration:
Permanent


Salary:
£35,000 - £50,000


Posting Contact Name:
Louise Bush


NATURE OF WORK:

Advanced Bacterial Sciences (ABS) is a rapidly-growing, pioneering enterprise providing environmentally and ecologically friendly microbial products for the bioremediation of a wide range of environmental pollution problems.

ABS is leading a number of ongoing and future projects on the development, trials and production of bioremediation products applicable to real-world settings.

ABS is offering a position for a full-time Senior Molecular Scientist to join the Molecular Laboratory in the Science and Innovation department.

The post-holder will be leading the design and implementation of the company's molecular analysis procedures and protocols for various projects in the Science & Innovation department, involving but not limited to genomics and genetics analysis from environmental samples (soil water and agricultural slurry): microbial community analysis, pathogen detection, gene quantification, species identification, metagenomics and transcriptomics.

DUTIES AND RESPONSIBILITIES OF THE POST:
The post-holder will be expected to lead and be a mentor on a variety of molecular biology, biochemical and microbiological methodologies across a wide range of projects


The role holder will:

• Provide scientific inputs and technical leadership on various molecular methods for all projects.
• Use various cell and molecular biology techniques and lab information management systems (LIMS) to ensure projects move forward within the expected timelines and specifications.
• Have plenty of experience with library preparation for Oxford Nanopore technologies.
• Develop efficient workflow systems with available resources and instruments.
• Implement methods and improvement procedures and methodologies.

Provide expertise on molecular biology, including investigation of negative/uncertain results and improvement of analytical methods.

• Analyse and interpret complex genomic data, assess QC data and prepare reports of key outcomes/results.
• Be proactive and use in depth internal and external knowledge to identify process improvement opportunities and implement new ways of working that have a direct impact on productivity and/or quality.
• Lead projects that result in benefits to key molecular analytical processes, such as reduction of service lead time & cost, improvement of data quality and extension of service areas
• Support the Product Development team and troubleshoot arisen issues relevant to molecular biology.
• Stay current with relevant scientific literature and new technologies to identify opportunities for improvement.
• Be a role model within the group.
• Train and mentor junior team members, providing guidance and support as needed.
• Communicate analysis findings and information in a clear, easytounderstand manner to other scientists and nonexperts in the company.
• Use resources effectively, while maintaining high standards for your team
• Be a champion in operational delivery and help direct daytoday laboratory activities and report on milestones delivery.
• Show high levels of motivation and demonstrate a positive, cando attitude in your daily tasks.
• Provide periodic reports and agree on workflow systems with the line manager to ensure an aligned understanding on the workload at each step.

MAIN WORK ACTIVITIES:

• Design, execute, analyse and interpret molecular biologybased assays to assess gene editing events (Primer design, PCR, qRTPCR, ddPCR, Sanger sequencing, NGS etc).
• Be familiar with a wide range of DNA analysis software and experienced with using various bioinformatics tools and data analysis packages.
• Perform regular inventory checks on laboratory supplies.
• Produce, maintain and update COSHH and Risk Assessment documents.
• Provide support to other members of staff.

KNOWLEDGE AND EXPERIENCE:

• PhD in molecular biology or related field (essential)
• Strong knowledge and experience with a range of sequencing techniques, software and databases, including but not limited to PCR, Sanger sequencing, NGS library preparation, whole genome sequencing and assembly(essential)
• Experience with method optimisation and validation (essential)
• A minimum of 5 years experience working and managing a commercial molecular biology laboratory and leading teams (essential).

COMPETENCIES/KNOWLEDGE AND SKILLS:

• Highly motivated and fastlearning individual looking to pursue a longterm career in molecular biology.
• Excellent communication and interpersonal skills, with the ability to communicate complex scientific concepts and results to a range of audiences.
• Seniority and strong exper