Clinical Research Facility Laboratory Coordinator - London, United Kingdom - Guy's and St Thomas' NHS Foundation Trust

Guy's and St Thomas' NHS Foundation Trust

Verified Company

London, United Kingdom

2 weeks ago

Posted by:

Tom O´Connor

beBee Recruiter

Description

This unique post offers an exciting opportunity to work as the Laboratory Coordinator in the NIHR Clinical Research Facility (CRF) at Guy's and St.

Thomas' NHS Foundation Trust.

The CRF Laboratory provides a comprehensive and high quality service including sample reception, preparation, processing, storage and shipment for samples collected as part of a complete portfolio of clinical trials implemented at the CRF ranging from First in Human (FIH) through to innovative phase 3 trials, and experimental non-IMP studies across a combined adult and paediatric service

The post holder will have knowledge of a range of pre-analytical processing procedures and will be responsible for overseeing the processing and storage of clinical trial samples to the highest standard

This includes:
- receiving, sorting, labelling and processing samples;
- resolving issues such as mislabelled or missing specimens;
- maintaining study data documentation;
- overseeing laboratory checks;
- facilitating scheduled internal audits;
- performing quality control checks on routine equipment;
- completing feasibility assessments and laboratory costings;
- contributing to COSHH and Risk Assessments (as required and appropriate);
- dealing with enquiries;
- preparing weekly laboratory work schedules.

The R&D Department at Guy's & St Thomas' NHS Foundation Trust (GSTFT) is one of the focal points for innovative research in London through its nationally recognised research portfolio and research infrastructure.

We are systems leaders in NHS research with strong strategic partnerships across the National Institute for Health Research (NIHR), Department of Health & Social Care (DHSC) and the Health Research Authority (HRA) and are active members of the organisations such as the Shelford Group, University Hospitals Association (previously AUKUH) and UKRD.

Research is a top priority for the Trust which in 2021/22 was the top NHS organisation nationally for the number of NIHR portfolio studies open (417) and was the top recruiting organisation in South London (third nationally) recruiting over 19,000 participants into NIHR portfolio studies.

Our research infrastructure includes our NIHR Clinical Research Facility (CRF) located St Thomas' Hospital, Guy's Hospital, Evelina London Children's Hospital and the Royal Brompton Hospital; the Guy's Phase I unit is an MHRA Accredited Phase I Unit (1 of only 2 NHS managed Units in England).

Within the Biomedical Hub at Guy's Hospital, the NIHR CRF is co-located with our Advanced Therapies Manufacturing (GMP) Unit; the Advanced Therapies Accelerator houses our Immune Monitoring Platform and Genomics Platform.

Coordinate and support the laboratory activity within the CRF laboratories on the 15thfloor of Tower Wing at Guy's Hospital (near London Bridge), the 4thfloor of St. Thomas' Hospital (near Westminster/Waterloo) and the 1stfloor of Evelina London (on St. Thomas' campus).
Manage the flow and organisation of work coming through the CRF lab, ensuring that work is carried out in a timely and efficient manner, in accordance with the laboratory manual and to the appropriate standards and regulations for research and the use of human tissue.
Purchase generic laboratory consumables using the CRF standard stock order procedure. Ensure all sample records are adequately stored and accessible by members of the research teams.
Track laboratory usage and provide reports on activity and temperature excursions to the CRF Management Team, study teams, sponsors and other teams as needed.
Ensure personal, staff and laboratory users appropriate handling, use and disposal of patient/participant tissue in accordance with the Human Tissue Authority (HTA) guidelines.
Carry out sample receiving, preparation, processing, coding, logging and shipping, as set out in the study protocol and laboratory manual, adhering to current ICH Good Clinical Practice (ICH GCP) guidelines and the Human Tissue Act.
Understand all new research protocols and lab manuals, identifying any aspects that may require additional feasibility testing or additional training for laboratory and research staff
Contribute to the costing of all studies using the CRF laboratories.