Research Associate - Hammersmith, United Kingdom - Imperial College London

Tom O´Connor

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Tom O´Connor

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Description
Research in the Division of Neuroscience addresses mechanisms that underpin nervous system functions and diseases.

Investigators in the Division are exploring these through combinations of neurophysiological, anatomical, molecular, cellular and computational approaches, using pre-clinical models and clinical studies.


Exciting research developments have placed the role of axonal signalling and transcriptional regulation at the centre of the capacity of axons to re-grow after spinal cord injury.

These include work from our laboratory (see Di Giovanni S, on PubMed).

Given that neurological recovery and axonal regeneration are not possible following a spinal injury, understanding how the re-growth of injured axons is controlled is key to enhancing axonal regeneration and potentially functional recovery.

Axonal signalling and metabolic control seem important for modulating the complex gene expression program necessary for the regrowth of an axon.

However, the role of environmental factors in signalling and metabolic pathways in axonal regeneration remains obscure.


The post is funded by funds to Di Giovanni's lab to investigate the molecular and cellular underpinnings of regenerative failure after nerve and spinal cord injuries.


Duties and responsibilities:


The Research Associate will be expected to generate data of high quality that can be submitted for publication to high-profile refereed journals and to attract external research funding.


Essential requirements:


  • Practical experience within a research environment and/or publication in relevant and refereed journals
  • Experience in dealing with a diverse scientific environment
  • Practical experience in a broad range of techniques including related to neurobiology and immunology
  • Practical experience within a research environment and/or publication in relevant and refereed journals
  • Knowledge of gene expression analysis
  • Knowledge of research methods and statistical procedures
  • Knowledge of research immunoblotting Knowledge of in vivo animal experimentation, preferentially nerve and spinal injuries
  • Ability to conduct a detailed review of recent literature
  • Creative approach to problemsolving
  • Excellent verbal and written communication skills and the ability to deal with a wide range of people
  • Ability to organise own work with mínimal supervision

Further information:

This is for 3 full time, fixed term positions for up to two years each. This position will be based at the Hammersmith Campus.

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