Radiopharmaceutical Technologist - Manchester, United Kingdom - The Christie NHS Foundation Trust

The Christie NHS Foundation Trust

Verified Company

Manchester, United Kingdom

3 days ago

Posted by:

Tom O´Connor

beBee Recruiter

Description

Consideration would be given to a less experienced applicant to join the team as a trainee.

This position is a 12 month temporary contract to cover maternity leave in the department*The Christie is one of Europe's leading cancer centres, treating over 60,000 patients a year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 15% patients are referred to us from other parts of the country. We provide radiotherapy through one of the largest radiotherapy departments in the world; chemotherapy on site and through 14 other hospitals; highly specialist surgery for complex and rare cancer; and a wide range of support and diagnostic services. We are also an international leader in research, with world first breakthroughs for over 100 years. We run one of the largest early clinical trial units in Europe with over 300 trials every year. Cancer research in Manchester, most of which is undertaken on the Christie site, has been officially ranked the best in the UK.

The Radiopharmacy was commissioned in 2009 and operates under two MHRA licences: Specials and Wholesale Dealers.

The Christie Radiopharmacy supplies radiopharmaceuticals to nine Nuclear Medicine departments and produces more than 7,000 vials per year, making it the largest Radiopharmacy in the North West region.

The Christie Radiopharmacy is also pioneering the use of Ga-68 radiopharmaceuticals and plays a key role supporting the NET service (ENETS Centre of Excellence).

DUTIES AND RESPONSIBILITIES
Regional Radiopharmacy

To be part of the team that carries out the daily production of radiopharmaceuticals within the Regional Radiopharmacy, in compliance with the requirements of The Human Medicine Regulations 2012, The Ionising Radiation (Medical Exposure) Regulations 2017, The Ionising Radiations Regulations 2017 and The Environmental Permitting Regulations

This includes:
Receipt of orders from customer departments

Preparation of the Radiopharmacy prior to each production run

Preparation of materials prior to the twice-daily Radiopharmacy production runs, including radionuclide generators

Participation in the complex processes for production of Tc-99m labelled radiopharmaceuticals using aseptic techniques, and working with due speed and efficiency.

Participation in the complex processes for production of Ga-68 and In-111 Octreoscan for same-day administration to Christie patients, using aseptic techniques

Packaging and dispatch of QC products to other hospitals, including liaison with drivers

Decontamination and cleaning of the Radiopharmacy post production, including tidying of waste and restocking of consumables

Packaging and return of used radionuclide generators to manufacturers

Production of the documentation for all the above processes (in compliance with GMP and data integrity principles)

Proposes changes to policies and procedures

Acts as in-process checking technician for the Radiopharmacy routine service and maintain this practice in accordance with local policy

Quality control

Carries out the programme of quality control of radiopharmaceuticals produced within the Regional Radiopharmacy, in compliance with the requirements of the Medicines Act

This includes:
Analysis of radiochemical purity using chromatography techniques (ITLC and HPLC)

pH testing

Radionuclidic purity testing

Analysis of particle sizes via optical microscopy and filtration techniques.

Analysis of endotoxin levels

Ensuring that working areas are cleared after each operatio

Environmental and microbiological monitoring

Participates in the programme of environmental and microbiological monitoring of the Radiopharmacy and blood labelling suites, to include:
Air quality and air flows

Microbiological contamination

Periodic monitoring of aseptic compliance for each member of staff

Integrity of air seals in the blood labelling suit

Regional blood cell labelling service

In the absence of the Senior Radiopharmaceutical Technologist, to be responsible on a day to day basis for the operation of the Regional blood cell labelling service, including:
Aseptic preparation of radio-labelled red and white blood cells, in multi-stage patient-critical procedures, prior to re-injection of the cells into patients for diagnostic scanning purposes

Liaison with customer departments for scheduling, transportation of blood to and from the customer department, and other arrangements

Management, supervision and training of staff

Deputises for the Senior Radiopharmaceutical Technologist in their absence.

Assists in the training of new staff and supervises the work of more junior members of the department

Stock control

Responsible for stock control and ordering of pharmaceutical products, including:
Pharmaceutical products, chemical reagents, and disposable items used in the radiopharmacy and associated areas

Consumable items for the Clinical Isotopes Department

Orders stock items fo