Principal Bioinformatician- Cancer Research - Cambridge, United Kingdom - Wellcome Sanger Institute

Wellcome Sanger Institute

Verified Company

Cambridge, United Kingdom

2 weeks ago

Posted by:

Tom O´Connor

beBee Recruiter

Description

Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity's greatest challenges.

About the Role:

We have an exciting opportunity for a Principal Bioinformatician to join our Experimental Cancer Genetics group led by David Adams on a permanent contract.

About Us:

We aim to identify cancer genes and to understand their function using approaches such as large-scale sequencing and genome editing.

We are also interested in how genes interact to promote cancer development, and how these interactions may be exploited for therapy.

Examples of recent studies include the deep saturation genome editing of cancer genes to facilitate the identification of germline cancer predisposing alleles, and large-scale combinatorial CRISPR screens to define synthetic lethal interactions.

We are also performing large-scale sequencing of rare skin tumours, and as part of a cross-species project, we are sequencing thousands of tumours from both dogs and cats, which were collected as part of their clinical care with the aim of identifying cancer causing exposures.

The group is a mixture of pure wetlab, mixed wet/dry lab students and postdocs; with the informatics team that you will lead currently including a Principal Software Developer, another Principal Bioinformatician, a Senior Bioinformatician and two Bioinformatician which you will line manage.

Key Responsibilities of the role:

Defining requirements for Experimental Cancer Genetics Group and developing software tools to meet these requirements, making changes where appropriate.
Providing timeline estimations for defined product delivery and plan and organise own work to meet the agreed deadlines
Seeking new software technology and techniques that can support various projects in the team
Supporting the Informatics team and line managing 2 bioinformaticians
Influencing other developers on technical points and advances

About You:

You have good communication skills and be able to understand the scientific background and technical detail of the team's projects.

You will be proficient at devising and implementing software solutions and statistical analysis and balancing expectations.

You will have the opportunity to join a multi-disciplinary team and to work across the Institute to support technological advances.

This is an excellent opportunity for you to demonstrate your software/programming skills and contribute to science in cancer research.

Essential Skills:

A degree or further degree related to biology/genetics/computer science ideally at PhD level or equivalent experience
Strong programming skills
Experience of working with Git
Experience of other languages and development tools such as Java, Python, and SQL
Strong design and analysis skills including object orientated software development
The ability to think laterally in order to combine disparate technologies
The ability to rapidly troubleshoot and resolve issues in high throughput 24/7 systems
A working knowledge of relational database systems including MySQL
Experience of researching/using/supporting external software packages
Ability to rapidly attain new technical skills and understanding of new concepts
Ability to work with a high degree of thoroughness, independently or part of a team
Strong interpersonal skills with the ability to communicate with people from a wide variety of disciplines
Ability to understand new scientific processes via communication with laboratory scientists
Ability to develop collaborations with internal and external groups
Excellent, broad based and selfreliant problemsolving skills
Good time management skills leading to high quality solutions within often short timeframes
Strong influencing skills
Demonstrates inclusivity and respect for all

Other Information:

Salary per annum:
£52,152-£61,957

Application Process:

Closing Date: 1st December 2023

Working at Wellcome Sanger:

Our flexible-hybrid working environment is designed to support a healthy work-life balance.

This means you can work flexibly with a combination of working from home, and working from our Campus to allow you to focus on being productive and part of the team while enjoying the benefits of working flexibly.

We aim to attract, recruit, retain and develop talent from the widest possible talent pool, thereby gaining insight and access to different markets to generate a greater impact on the world.

We have a supportive culture with the following staff networks, LGBTQ+, Parents and Carers and Race Equity to bring people together to share experiences, offer specific support and development opportunities and raise awareness.

The networks are also a place for allies to provide support to others.

We want our people to be whoever they want to be because we believe people who bring their best selves to work, do their best work.

That's why we're committed to creating a truly inclusive culture at Sanger Institute.

We will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.

Our Benefits:

We are proud to deliver an awarding campus-wide employee wellbeing strategy and programme.

The importance of good health and adopting a healthier lifestyle and the commitment to reduce work-related stress is strongly acknowledged and recognised at Sanger Institute.