Associate Scientific Director, Translational Quantitative Pharmacology - London - Merck KGaA

Description

Job Id

291428

Feltham, London, United Kingdom

Job Type

Full-time

Work Your Magic with us

Ready to explore, break barriers, and discover more? We know you've got big plans – so do we Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

Your role:

As the Associate Scientific Director in Translational Quantitative Pharmacology, you will play a pivotal role in shaping Model Informed Drug Development (MIDD) strategies throughout the R&D lifecycle. You will be responsible for all TQP assignments either executed internally or in collaboration with external TQP related CROs by providing close scientific and technical supervision. You will be expected to manage multiple projects simultaneously and participate in discussions and presentations. You will be responsible for developing quantitative mechanism-based PK/PD models that inform critical decisions from lead optimization to clinical proof of concept, particularly within the immunology and oncology pipelines. Your role will also involve performing human PK predictions and designing pre-clinical PK/PD experiments to support development efforts. You will interact with project team members, communicate results of model-based analyses and foster a collaborative environment. By implementing innovative modeling and simulation platforms, you will ensure that the right drug is administered to the right patient at the right dosage. Your contributions will extend to preparing and presenting documentation for internal and external stakeholders, enhancing our program strategy and impact.

Who you are:

• You have a minimum of 5 years of experience in industry and/or academia in a relevant field.
• You hold a PhD in Pharmacokinetics, Pharmaceutical Sciences, Biomedical/Chemical Engineering, Applied Mathematics, or a related discipline, demonstrating a proven track record in modeling and simulation.
• You are fluent in English and possess sound knowledge of Quantitative Systems Pharmacology principles.
• You have hands-on experience in mathematical modeling of pharmacologic effects with mechanism-based models using software such as MATLAB/SimBiology, NONMEM, or R.
• You have applied translational PK/PD modeling and simulation, including QSP models, in research and early clinical development.
• You understand the basic principles of biology and pharmacology, particularly in oncology, immunology, or immuno-oncology.
• You are capable of rapidly assimilating complex biological knowledge and transforming it into multi-scale mathematical models.
• You possess excellent communication skills, enabling you to translate modeling outcomes effectively for research and development projects.

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress

and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity

US Equal Employment Opportunities

The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.

Notice on Fraudulent Job Offers

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Applicant Profile

Along with our brand-new career site, we've also revamped our application process. If you've applied for a position before April 16th 2025, you can log into your old profile to see the status of past applications. For the application you've will completed, and any in the future, you can create a new profile to check in on your status.

WHAT WE OFFER

Money makes the world go round. But at our company there's more than just financial rewards. We offer a range of attractive benefits to help you work your magic.

Saving & Finacial

Our 401(k) Plan includes a generous company-matching contribution and an additional discretionary contribution each year.

We also provide tax-advantaged accounts for you to save for healthcare, commuting expenses, company-provided and buy-up life insurance to help you protect your financial future.

Health & Wellness

We offer comprehensive medical, dental, & vision coverage-including virtual care through Telehealth & free behavioral health counseling sessions through our Employee Assistance Program.

We also offer a wellness incentive program and personalized support to help you navigate and use your benefits.

Voluntary Benefits

Our voluntary benefits provide additional protection from the high costs of healthcare not covered by health insurance.

We also have discount programs that offer exclusive savings on everything from auto, home, and pet insurance to low-interest personal loans.

Work/Life Support

We have several programs to support your work/life balance, including generous paid time off, back-up day care services, education assistance, and more.

OUR RECRUITING PROCESS

Depending on the position (level, functional area, country) the process can vary slightly.

You apply

Complete your online application for your preferred role(s) that match your interests and qualification. If you cannot find a suitable role please join our Talent Zone and stay connected for your next career opportunity.

We screen

We review your application and if we determine that you are a good fit we will move you to the selection process.

We assess

You are interviewed by phone, via video and/or face to face.

Mutual agreement

Ideally you are the perfect match for us We hope you consider us as your new employer.

Work your magic

To guarantee you a smooth start our onboarding preparation begins.

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