Mnd Institute Research Assistant - London, United Kingdom - King's College London

King's College London

Verified Company

London, United Kingdom

5 days ago

Posted by:

Tom O´Connor

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Description

Job description

We are looking for a skilled research assistant with a molecular biological background to join the brand new MND Institute at King's College London.

We are investigating amyotrophic lateral sclerosis-frontotemporal dementia (ALS-FTD). You will be using CRISPR to gene edit human stem cells to model ALS-FTD in vitro. This is part of a large UK-wide initiative to accelerate translation to therapies for devastating neurodegenerative diseases.

This work will entail the use of directed differentiation using genetic cassettes to facilitate isogenic studies of derived neurons and microglia.

You must have molecular biological knowledge and experience working in the neuroscience field. CRISPR experience is essential.

This post will be offered on a fixed-term contract to 31st January 2025

This is a full-time post - 100% full time equivalent

Key responsibilities

Maintaining human iPSCs, neurons and microglia
Site directed mutagenesis
RNA extraction, qPCR
Brain histology
Manuscript writing and figure preparation
Presenting at regular lab meetings
The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post._

Skills, knowledge, and experience

Essential criteria