Postdoctoral Research Scientist or Research - Babraham, United Kingdom - Babraham Institute

Babraham Institute

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Babraham, United Kingdom

3 weeks ago

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Tom O´Connor

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We are seeking a Postdoctoral Research Scientist or Research Assistant with a background in immunology and/or molecular biology to lead an exciting new collaboration between the labs of Arianne Richard (Immunology Programme) and Peter Rugg-Gunn (Epigenetics Programme) at the Babraham Institute.

Combining the expertise of these two groups, the recruited scientist will investigate the role of epigenetic memory in guiding functional divergence of particular T cell subsets dependent on stimulation history.

This project will specifically test whether differentiation and functional responses of effector T cells are impacted by epigenetic memory in their precursor states.

To this end, the appointed scientist will i) Compare the epigenetic and functional properties of effector T cells and precursors with different stimulation histories; ii) Test and refine an in vitro system to interrogate causal relationships between epigenetic modifications and T cell effector function.

The exciting implication of this work will be to generate new insight into how prior experiences within a T cell lineage shape effector responses and whether this behaviour is encoded by epigenetic memory.

This is important because T cell-intrinsic effects of prior exposures have the potential to contribute to differences in immune responses that accumulate over the lifecourse.

In addition, characterising the epigenetic effects of stimulation history can ultimately influence the rational design of T-cell-targeting vaccination.

A full job specification and role requirements can be found attached to this vacancy.

For more information on the work of the groups, please visit:
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Applicants for the Postdoctoral Research Scientist position must hold a PhD or have their thesis submitted when commencing the post.

Please note that you will be appointed on the starting salary of £33,500 per annum, if you have not yet been awarded your PhD.

All newly appointed postdocs will commence on the salary/scale point that reflects the number of years' post-PhD experience they hold on 30th June in the calendar year they commence employment.

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NO AGENCIES PLEASE

The Babraham Institute holds a silver Athena SWAN award and is committed to promoting and developing a culture of excellence, diversity and mutual respect that supports the Institute's ambitions and attracts highly motivated and talented people. The Babraham Institute is a Disability Confident Employer and has a positive approach to employing disabled people._