Research Fellow in Structural Biology of Rna - Birmingham, United Kingdom - Springer Nature

Springer Nature
Springer Nature
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Birmingham, United Kingdom

2 weeks ago

Tom O´Connor

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Tom O´Connor

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Description

Research Fellow in Structural Biology of RNA:

  • Employer
  • University of Birmingham
  • Location
  • University of Birmingham
, Edgbaston, Birmingham UK
  • Salary
  • Full time starting salary is normally in the range £34,980 to £44,263
  • Closing date
  • 20 Feb 2024
  • Discipline
Biomedicine, Life Science
Job Type
Researcher
Employment - Hours
Full time
Duration
Permanent
Qualification
PhD
Sector
Academia- You need to sign in or create an account to a job.


Overview


Our international group of highly motivated and interdisciplinary structural biologists is expanding We are looking for a research fellow fascinated by the structural basis of molecular functions.

You will study the structure and dynamics of RNA both in isolation and in complex with its cellular partners.

The focus will be on understanding how RNA modifications impact its structure, function and interactome, with the aim of establishing new drug targets in cancer and fungal infections.

Being this a timely, expanding research area, there is opportunity for methodological developments. We offer unique access to first-class instrumentation for structural biology. At the national centre for biomolecular NMR spectroscopy in Birmingham (HWB-NMR), we host the best biomolecular NMR equipment available in the UK, comprising 1000, 900 and 800 MHz spectrometers equipped with cryoprobes and MAS probes for both solution
- and solid-state NMR, as well as an incoming 1.2 GHz spectrometer expected in 2025. At the Midlands Regional Cryo Electron Microscope Facility in Leicester, you will have access to a 300kV Titan Krios G3 cryo-electron microscope with a direct electron-detecting camera. We have BAG access to the synchrotron at DIAMOND for small angle scattering, X-ray crystallography and many more X-ray based techniques. Fully equipped biochemistry and molecular biology laboratories, as well as extensive equipment for in cellulo work and light microscopy are available. This interdisciplinary research environment will provide you with unique development opportunities.


Our globally-operating research group is embedded in a vibrant community of world-renowned scientists in the fields of genome biology, cancer research and microbiology, as well as RNA engineering.

We believe in interdisciplinarity and we strive to integrate structural biology with functional studies in cells and whole organisms, as well as with drug design and molecular engineering.

If you are curious, motivated and ready for challenge to discover the rules of nature by biophysics, you can't miss this opportunity


Summary of Role

  • Work within specified research grants and projects and contribute to writing bids
  • Operate within area of specialism
Design and perform experiments

  • Analyse and interpret research findings and results
  • Contribute to generating funding
  • Contribute to licensing or spin out deals with demonstrated commercial success (such as revenues, asset or company sales, IP generated) and/or public understanding of the discipline or similar.

Main Duties

  • Project planning: set milestones and measurable deliverables.
  • Plan and perform experiments and data analysis.
  • Trouble shoot experiments; develop or adapt techniques, models and methods.
  • Interpret the data, periodically evaluate the research plan and adjust as needed.
  • Develop strategies to project success.
  • Critically analyse results in the broader context.
  • Communicate research outputs.
  • Contribute to the research group activities and duties.
  • Provide guidance as required to support staff and any students who may be assisting with research.

Person Specification

  • PhD (or near to completion) in Biophysics/ Biochemistry/ Chemistry/Chemical Biology/ Structural Biology or related areas. Or, equivalent qualifications.
  • Genuine interest in molecular mechanisms.
  • Excellent analytical skills.
  • Proven experience in structural biology, both in data acquisition and analysis.
  • Track record of working successfully in a biochemical laboratory.
  • Creative and outcome oriented.
  • Enthusiastic to work in a competitive, international environment.
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