Lc-ms Research Scientist - Slough, United Kingdom - VRS Recruitment

VRS Recruitment
VRS Recruitment
Verified Company
Slough, United Kingdom

1 month ago

Tom O´Connor

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Tom O´Connor

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Description
An excellent opportunity for a Research Scientist to contribute to early drug discovery in the fields of Biotransformation & Enzymology


You will be responsible for providing analytical support across a broad range of NCEs from early stage, Hit-ID to pre/ post clinical evaluation.

Your primary role will be to generate LC-HRMS data from the analysis on in vivo/ in vitro samples contributingto metabolic profiling activities.

You will be tasked with understanding the metabolic fate of NCEs and providing feedback to medicinal chemists regarding drug design iterations.


Essential requirements:

  • Minimum PhD graduate OR BSc/ MSc in Chemistry/ Biochemistry with 3+ years industry experience in a drug discovery setting.
  • Extensive knowledge & experience in HPLC, uPLC, LC
  • HRMS
  • Experience in general in vitro lab skills
  • An excellent understanding of metabolism, DMPK, ADME
  • Familiarity with Thermofisher LCMS suite of equipment would be advantageous

Please note this is an initial 12 month contract.

  • Key words: Pharmaceutical, biopharmaceutical, Biotransformation, Enzymology, Metabolism, Metabolic profiles, NCEs, New Chemical Entities, LC-MS, LC-HRMS, HPLC, UPLC, Drug Discovery, in vitro, in vivo, Thermofisher, Waters, Agilent, Oxfordshire, Berkshire,London, Oxford, Reading, Slough, VRS8194SE_
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