Yashwani Malik

I am a microbiologist, curious about novel antimicrobials for clearing biofilms of superbugs. I have expertise in microbial culture maintenance, phage therapy, and protein purification. Proficient in data analysis, lab protocol optimization and compliance, I excel at developing efficient processes and training teams. With a problem-solving mindset and a passion for innovation, I aim to leverage my skills to develop sustainable solutions for combating microbial infections and their biofilms that helps in advancing global health

I worked as a Scientist at Yashraj Biotechnology Ltd., India. As a member of the R&D Downstream Processing team, I specialized in the purification of various recombinant and native antigens and antibodies from a range of body fluids. My responsibilities included optimizing and using FPLC, to achieve high-purity product isolation. I collaborated closely with cross-functional teams to develop and refine purification protocols, ensuring scalability and reproducibility for large-scale production. Additionally, I was responsible for analysing and interpreting purification data, troubleshooting processes, and maintaining detailed documentation to support regulatory submissions and quality control.

I have Masters of Research in Molecular Microbiology from Nottingham Trent University. During my degree I worked on a project to find treatment against the multi drug resistant bacteria Serratia marcescens. The project focuses on find treatment against the multi drug resistant pathogen Serratia marcescens using phage and enzyme therapy. It involves cloning and purifying the depolymerase enzyme encoded by bacteriophages that infect the antibiotic-resistant Serratia marcescens and using it as therapeutic against the pathogen. These depolymerase enzymes degrade the bacterial capsule and leave them vulnerable to the host immune system. The efficacy of phages was tested in wax moth models against the pathogen.