#immunotherapeutics
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Harnessing the non-complement role of factor H and properdin for cardiovascular and onco-immunotherapeutics
Sashmita Rout · Factor H · in complement activation inhibit the assembly of the alternative pathway C3 and C5 convertase enzymes via competition with factor B for C3b binding . Factor H facilitates the disassembly of the convertases by displacing bound factor Bb 9decay accelerating activity. Fa ...
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