- Developing an oligonucleotide synthesis pipeline to serve critical R&D projects.
- Developing synthesis methodologies for complex, modified and long DNA/RNA oligonucleotides.
- Improving purification and analytical workflows for synthesised oligonucleotides, introducing automation where possible.
- Analysing oligonucleotides by high-resolution CE, LC-MS and HPLC.
- Onboarding new technology and methods to improve operational effectiveness.
- Contributing to the scientific and technical training of the team.
- Promoting a safe working environment for all team members and a culture of continuous improvement for health & safety.
- Preparing clearly articulated progress reports and keeping well-organised experimental records.
- Working and communicating effectively across a number of research and development groups
- BSc, MSc or PhD degree in chemistry with industrial or equivalent experience.
- Strong experience in oligonucleotide synthesis
- Nucleosides, phosphoramidites and triphosphates synthesis experience would be a plus.
- Practical knowledge of small molecules and oligonucleotide analysis and purification.
- Strong problem solving and analytical skills.
- Strong attention to detail and a high level of organisation.
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Development Scientist - Didcot, United Kingdom - Oxford Nanopore Technologies
Description
Oxford Nanopore Technologies is headquartered at the Oxford Science Park outside Oxford, UK, with satellite offices and a commercial presence in many global locations across the US, APAC and Europe.
Oxford Nanopore employs from multiple subject areas including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialisation. The management team, led by CEO Dr Gordon Sanghera, has a track record of delivering disruptive technologies to the market.
Oxford Nanopore's sequencing platform is the only technology that offers real-time analysis, in fully scalable formats from pocket to population scale, that can analyse native DNA or RNA and sequence any length of fragment to achieve short to ultra-long read lengths. Our goal is to enable the analysis of any living thing, by anyone, anywhere
In this exciting and challenging role you will assist in expanding the nucleotide and oligonucleotide synthesis capabilities aimed at research and development within a newly established oligonucleotide facility.
Depending on experience, you will take on technical leadership roles and work closely with other members of the oligonucleotide facility team and develop new synthesis, purification and analytical methodologies/workflows for a wide range of critical long and modified DNA/RNA oligonucleotides.
In addition, you will play a collaborative role in the decision making of strategic objectives that influence future projects, the team and the company.
Tasks Will Include:
What We're Looking For...
Training will be given and, as such, a willingness to learn and develop is essential.
Applications are encouraged from highly motivated individuals who enjoy taking on new challenges, are quickly adaptable in an exciting and fast-paced environment, and who perform well under pressure.
We offer outstanding benefits to include an attractive bonus, generous pension contributions, private healthcare and an excellent starting salary. Based within beautiful, landscaped surroundings with tree-lined walks, water features and a lake, all of which make for a wonderful working environment.
If you are looking to utilise your skills to really make a difference to humankind, then consider joining our team and apply today
Please note that no terminology in this advert is intended to discriminate on the grounds of a person's gender, marital status, race, religion, colour, age, disability or sexual orientation. Every candidate will be assessed only in accordance with their merits, qualifications and abilities to perform the duties of the job.
About Us
Oxford Nanopore's goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere. The company has developed a new generation of nanopore-based sensing technology enabling the real-time, high-performance, accessible and scalable analysis of DNA and RNA. The technology is used in more than 100 countries to understand the biology of humans and diseases, plants, animals, bacteria, viruses and whole environments.
Oxford Nanopore was founded in 2005 as a spin-out from the University of Oxford and now employs over 1000 employees around the world.
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