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    PhD Studentship - London, United Kingdom - UCL Eastman Dental Institute

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    Fixed-term
    Description
    About the role

    The PhD Student will be based at the Rayne building, 5 University Street.

    The main purpose of this project is to work on the development of a novel therapy for antibiotic resistant Acinetobacter baumannii infections.

    The student will work closely with an MRC-funded team developing a monoclonal antibody treatment for A. baumannii.

    They will assess the efficacy of antibody to selected protein antigen targets at promoting bacterial killing using a combination of immunological assays and advanced microscopic techniques to measure at the molecular level formation of the Membrane Attack Complex on A.

    baumannii.

    By combining Brown's expertise in bacterial biology and immunology with the techniques available in the Hoogenboom laboratory this project will provide nanoscale characterisation of immune interactions on the A.

    baumannii bacterial outer membrane and obtain highly novel data on the functional consequences of antibody binding to different A. baumannii outer membrane target antigens.

    For more details, a job description and person specification can be accessed at the bottom of this page.

    General enquiries regarding the post can be made to Professor Jeremy Brown ().

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