Principal Bioinformatician - Cambridge, United Kingdom - Wellcome Sanger Institute

Wellcome Sanger Institute

Verified Company

Cambridge, United Kingdom

1 week ago

Posted by:

Tom O´Connor

beBee Recruiter

Description

Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity's greatest challenges.

About the Role:

We are seeking a Principal Bioinformatician to generate biological and therapeutic insights from complex and large-scale multi-dimensional functional and genomic datasets.

This will include access to unique datasets from systematic CRISPR screens in genomically-characterised cancer cell lines.

You will work in a team environment with cell biologists, biochemists, and other data scientists to deliver high value targets for drug development.

This an opportunity to develop transformative medicines for cancer patients at the interface of academic research and industry.

The project is funded by Open Targets which is a public-private partnership that uses human genetics and genomics data for systematic drug target identification and prioritisation.

This position will be for a 1 year fixed term contract.

About Us:

Many cancer patients have tumours which are resistant to existing treatments. Combination therapies aimed at inhibiting multiple targets can provide new treatments for patients and combat drug resistance. In this role, you will join a multidisciplinary team focused on identifying targets for combination drug therapies.

The Translational Cancer Genomics team, led by Dr. Mathew Garnett, investigates how genetic alterations in cancer contribute to disease and impact on response to therapy.

Our research integrates cancer genomics, cell biology and cancer therapeutics and employs cutting-edge experimental and data science approaches to tackle some of the biggest challenges in cancer.

You will be responsible for:

Using and developing a range of innovative bioinformatics approaches for the identification and prioritisation of combination drug targets. This will involve working as part of a multidisciplinary team including cell biologists and data scientists.

About You:

You will have an interest in using computational approaches to address fundamental question in cancer biology towards the development of new therapeutic strategies.

You should have a background in computer science, bioinformatics or related disciplines, and will ideally have experience in the analysis of cancer genomic or functional genomic datasets.

You will also be interested in working together with a multi-disciplinary team, demonstrate intellectual curiosity and the potential for developing your skills in new scientific directions.

Essential Skills:

A PhD or equivalent relevant experience in computational biology, bioinformatics, biostatistics or related scientific discipline
Training in statistical methods appropriate for biological research
Strong Experience in the analysis and modelling of signalling networks
Experience working in a research environment
An established track record of productivity through publications
Demonstrable proficiency in one or more scripting languages
Excellent communication and organisational skills.
Proven independent working style, technical problem solving, data analysis and generation of novel ideas
Motivation and ambition to make a personal contribution to GRL research.
Proven ability to work effectively within a team.
Ability to work multitask and organise own workload.
Good attention to detail and record keeping.
Demonstrates inclusivity and respect for all.
Highly developed problem solving skills

Other Information:

Salary per annum:
£52,152-£61,957 (dependent upon skills and experience)

Application Process:

Closing Date: 18th June 2023

Working at Wellcome Sanger:

Our flexible-hybrid working environment is designed to support a healthy work-life balance.

This means you can work flexibly with a combination of working from home, and working from our Campus to allow you to focus on being productive and part of the team while enjoying the benefits of working flexibly.

We aim to attract, recruit, retain and develop talent from the widest possible talent pool, thereby gaining insight and access to different markets to generate a greater impact on the world.

We have a supportive culture with the following staff networks, LGBTQ+, Parents and Carers and Race Equity to bring people together to share experiences, offer specific support and development opportunities and raise awareness.

The networks are also a place for allies to provide support to others.

We want our people to be whoever they want to be because we believe people who bring their best selves to work, do their best work.

That's why we're committed to creating a truly inclusive culture at Sanger Institute.

We will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.

Our Benefits:

We are proud to deliver an awarding campus-wide employee wellbeing strategy and programme.

The importance of good health and adopting a healthier lifestyle and the commitment to reduce work-related stress is strongly acknowledged and recognised at Sanger Institute.