- Isolation and culture of primary tissue.
- Immunohistochemistry and live cell imaging.
- Hormone secretion assays.
- Trouble-shooting and method development.
- Analysis and record-keeping.
Research Assistant - Oxford, United Kingdom - University of Oxford
Description
An exciting opportunity has arisen for a Research Assistant position in the Prof David Hodson group within the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) ).
The successful applicant will assist in ongoing projects studying glucagon-like peptide-1 receptor (GLP1R) and gastric inhibitory polypeptide (GIP) receptor signaling using novel fluorescent probes and models. The project will focus on understanding where GLP1 and GIP receptors are localized and how they signal in complex tissue. An important component of the studies will be to use advanced cell imaging, including confocal and super-resolution modalities. Projects will be complemented with human islets and pancreas sections where needed.
Although full training will be given in a variety of techniques, the person appointed will be expected to work independently on most tasks or in collaboration with the support of colleagues. Methods will include the preparation and analysis of samples for hormone secretion, RNA extraction, PCR, cloning and optical imaging.
The project will involve:
The position would suit a cell biologist with experience of imaging, molecular genetics and cell culture. A background in diabetes, metabolism or neuroscience is desirable, but not essential, as full support and training will be provided.
The position is full time and fixed term until 28/02/2029. The position will be based at OCDEM, Churchill Hospital, Oxford.
For informal enquiries, please contact Supprina Thebe at Please quote reference on all correspondence. As part of your formal online application, you will be required to upload a CV and supporting statement. Only applications received before midday on 30/04/2024 can be considered. Interviews are scheduled to be held on 22/05/2024
£32,332 to £38,205 per annum, Grade 6