Research Associate - London, United Kingdom - King's College London

Tom O´Connor

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Tom O´Connor

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Description

Job id:
Salary: £43,205 - £50,585 per annum, including London Weighting Allowance.

Posted: 21 May 2024.

Closing date: 16 June 2024.

Business unit:
Natural, Mathematical & Engineering Sci


Department:
Physics.


Location:
Strand Campus


Category:
Research.

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About Us


King's College London has one of the UK's best Physics Departments with the QS World University Rankings placing us in the top 10 universities in the country.


Our research-intensive department houses internationally renowned scientists working across diverse and interdisciplinary fields, including biological physics and soft matter, photonics and nanotechnology, the theory and simulation of condensed matter, theoretical particle physics and cosmology; and experimental particle and astroparticle physics.

About the role


We are seeking to appoint a biophysicist or a cell/molecular biologist (preferably with a PhD in Physics, Cell/Molecular Biology, Chemistry, Biochemistry, Bioengineering or related disciplines) with proved experience in any area of mechanobiology.


This project aims to investigate the molecular mechanisms by which extracellular mechanical forces travel long distances inside the cell to reach the nucleus on biologically-relevant timescales, and how mechanical forces activate force-induced transcriptional programmes.

The project can be attacked from different perspectives (single molecule, single cell, or tissue level) but in all cases requires extensive experience in the relevant mechanical techniques, according to each relevant length-scale.

The project is funded by the Wellcome Trust. The project will be developed between the Francis Crick Institute and the Department of Physics at King's College London.


Within King's, you will be part of the department of Physics, which belongs to the Faculty of Natural, Mathematical & Engineering Sciences (NMES).

Supporting our staff is important to us and we offer a range of provision including flexible working, caring support, and training opportunities.

The university is making significant investment in the Faculty and both student and staff numbers are growing. Our staff come from over 45 countries and around 56% of our students are from outside the UK.

Key responsibilities

Develop high quality research in the field of mechanobiology

Contribute to publications arising from this project

Contribute fully to developing and enhancing the research profile of the Department, Faculty, and University, including establishing a track record of high-quality publications

Use new research techniques and methods

Identify areas for research, develop new research methods and extend the research portfolio

About You

Essential criteria


  • Hold a PhD in Biophysics, Physical Chemistry, Cell/Molecular Biology, Biochemistry, Bioengineering or equivalent
  • Extensive demonstrable experience with mechanobiology, although we are open to different length-scales (molecular, cellular, tissue) and with the mastering of the relevant related techniques.
  • Programming skills/quantitative approaches
  • Experience in student supervision, grant writing and project design
  • Experience with light microscopy (confocal/spinning disk/superresolution) microscopy
Desirable criteria


  • Experience in protein design, cloning, expression and purification
  • Experience in Cell Biology (Cell culture, transfections, CRISPR, etc.)
  • Experience with single molecule mechanics (AFM, magnetic tweezers, optical tweezers)
  • Experience with cell mechanics (AFM, Cell Magnetic tweezers, cyclic stretching, microfluidics, etc) experiments
  • Experience in Mass spectrometry characterization of proteins
Further Information

We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community.

We are committed to working with our staff and unions on these and other issues, to continue to support our people and to develop a diverse and inclusive culture at King's.

Benefits of working at King's College London.

KCL provides an extensive and varied range of career-focussed training and on-the-job learning as follows:

We support staff to maintain a work/life balance

Flexible working, parental leave opportunities, and subsidised childcare costs.

Reduced membership rates for staff at gyms at three of our campuses

Employee Assistance Programme provides free, confidential advice on both home and work concerns

30 days annual leave (plus UK bank holidays and four additional concessionary closure days over Christmas)

Occupational pension scheme with generous employer contributions, and opt-in additional personal contributions

Season ticket loans and cycle-to-work scheme

Membership of My King's Discounts offering preferential rates to a wide range of groceries, holidays, entertainment, home, health, beauty and fashion

Full information on staff benefits:
Staff Benefits - King's College London (kcl.a

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