Brc Clinical Research Fellow - Liverpool, United Kingdom - The Clatterbridge Cancer Centre NHSFT
Description
CCC is now part of a Biomedical Research Centre (BRC) in partnership with The Royal Marsden, one of the most prestigious cancer centres in the world.
The applicant will collaborate with the Urology team (Lead Dr Alison Tree) as part of the research project.You will have the opportunity to be involved in recruiting and treating patients in urology trials, auditing, writing papers and reviews and there is the potential to present research work at meetings and conferences.
The position requires an ability to understand and use MRI imaging data and radiotherapy planning systems.
The applicant will learn to critically assess and analyse results from prostate radiotherapy trials; liaising across a range of clinical, academic and administrative staff throughout the Trust and the University of Liverpool.
Aim/Work stream 1:
The project will evaluate how different factors (including deprivation score and research funding) influenced recruitment into PIVOTALboost or PACE A, B and C trials UK wide.
Aim/Work stream 2:
The two PIVOTALboost RTQA benchmark cases will be evaluated against Simultaneous Truth and Performance Level Estimate (STAPLE) contours; the geometric variability will be compared with dose volume parameters, tumour control probability and normal tissue complication probability from re-planned individual submissions.
Aim/Work stream 3:
With in collaboration with the radiology team, AI generated boost contours are produced from BIOPROP cohort studies (Clatterbridge phase II cohorts, training set); from two PIVOTALboost trial centres, evaluate the AI generated contours with contours generated by PI and an expert panel (validation set).
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