Protein Scientist - Slough, United Kingdom - CK Science

    CK Science
    CK Science Slough, United Kingdom

    3 weeks ago

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    Description

    Protein Scientist

    CK Group are recruiting for a Protein Scientist to join a to join a global pharmaceutical company, based in Slough on a contract basis initially for 12 months

    Salary:

    Hourly £28.09 per hour PAYE / £38.24 per hour Umbrella

    Protein Scientist Role:

  • You will be responsible for expressing and purifying high-quality recombinant protein reagents to support novel world-leading antibody and NCE drug discovery platforms for a variety of exciting therapeutic projects.
  • You will have an excellent and proven track record of protein reagent delivery.
  • You will use your excellent practical skills, communication and team working abilities to drive innovative projects forward from the laboratory.
  • You will be responsible for clearly presenting work and engaging in discussion in a variety of cross-functional and external collaborator meetings.
  • Your Background:

    Candidates will have extensive experience (PhD holder or graduate with 4-5 years) in protein biochemistry, focusing on recombinant protein production, preferably in an industrial environment

    We are looking for candidates who are fully independent and competent in the following skill sets:

  • Molecular Biology (DNA manipulation techniques and comprehensive knowledge and experience with software used in manipulating protein and DNA sequences (VNTI) and molecular visualisation of proteins (PyMOL or similar).
  • Proficient in E.coli, insect and mammalian cell expression systems (and experience in 15N, 13C and 2H labelled expression in E.coli)
  • Fully independent in protein purification techniques (affinity, ion exchange, hydrophobic interaction chromatography, size exclusion chromatography, analytical SEC, UV-Vis spectroscopy, and protein refolding techniques) and extensive experience working with AKTA purification platforms and associated software.
  • Fully competent in protein characterisation techniques: SDS-PAGE, Western blot, analytical SEC, UV-Vis spectroscopy and UPLC.
  • Excellent biochemistry knowledge with hands on experience of protein labelling and characterisation.
  • Good understanding of recombinant protein expression systems and the molecular biology involved in generating expression constructs.
  • Company:

    Our client is a is a global biopharmaceutical company focused on creating value for people living with severe diseases in immunology and neurology now and into the future.

    Location:

    This role is based at our clients site in Slough. From a future date to be confirmed (mid-2025), the Company office premises will move to Windlesham, Surrey.