Research Assistant Neuronal Cell Biologist: - Oxford, United Kingdom - University of Oxford
Description
Full-time, Fixed-term for 2 years
Applications are invited for a Research Assistant neuronal cell biologist to work on a project to discover novel biomarkers of lysosomal dysfunction in Parkinson's disease.
The project, funded by the Michael J Fox Foundation and in collaboration with EndLyz, a new company within the Dementia Discovery Fund (DDF) portfolio, represents an exciting opportunity to undertake translation work at the interface between academic research and pharmaceutical target and drug discovery in an exceptional setting.
This work will develop novel biomarkers to better understand lysosomal dysfunction in Parkinson's by working with induced pluripotent stem cell (iPSC)-derived dopamine neurons generated from Parkinson's patients.
Duties will include undertaking laboratory experiments; interpretation of data; imaging analysis; generation and study of iPSC-derived neurons and cell lines; preparation of data for publication; study biomarker read-outs of endolysosomal dysfunction in cellular models of Parkinson's; contribute to wider project planning and determine the most appropriate methodologies to test hypotheses.
You will have excellent practical experience of working with induced pluripotent stem cell cultures and good knowledge of cellular models of neurodegenerative disease.
The ability to innovate, trouble-shoot technical problems, be meticulous in practical work and in record keeping is essential.
Applicants must hold, or be near completion of, a BSc/MSc in a relevant area of research and have experience in cellular neuroscience or molecular cell biology relevant to analysis of neuronal phenotypes.
Interviews are likely to be held on
the week beginning 22 April 2024.
We, as a Department and Community, will be considerate and welcoming of all people, regardless of race, ethnicity, religion, disability, sexual orientation and gender identity.
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