Cell Metrology Researcher - Leeds, United Kingdom - LGC Limited

LGC Limited

Verified Company

Leeds, United Kingdom

2 weeks ago

Posted by:

Tom O´Connor

beBee Recruiter

Description

There is an exciting opportunity to join the Cell Metrology team within the National Measurement Laboratory at LGC, based on Nexus, Leeds.

We are looking for an early career post-graduate cell biologist with flow cytometry experience who can assist in developing and improving quantitative methods for cell-based measurements, feeding into international standardisation initiatives.

Current research efforts are focused on optimising single cell measurements through the use of bio-imaging techniques such as confocal and widefield microscopy and FACS to identify key cell critical quality attributes.

This is an excellent opportunity for an enthusiastic scientist adept in FACS analysis to join a small new team addressing fundamental and emerging cell measurement challenges.

This individual will contribute to the design and development of proposals/projects for numerous customers both public and private sectors.

They will deliver government funded cell metrology research and commercial projects primarily using flow cytometry and cell sorting but also support confocal microscopy and cell culture for multiple projects.

Key responsibilities and accountabilities

Independent daytoday planning and delivery of work.
Responsible for conducting analytical work including method development and validation, biological specimen preparation, data acquisition and subsequent data analysis for flow cytometry and cell sorting.
Create working instructions and maintain laboratory notebooks.
Contribute to scientific writing to produce publications and represent the team in internal and external events.
Contribute to the maintenance of quality, health, and safety records, adhering to ISO9001 quality management system.
Participate in maintaining cleaning procedures, ordering consumables and general upkeep of the laboratory.
Responsible for routine maintenance to determine system performance, service contracts, operation and troubleshooting of flow cytometry and cell sorting instruments.

Qualifications

Knowledge, Experience and Technical Skills Required

Essential:

Proficient in running, troubleshooting flow cytometry and cell sorting instrumentation.
Extensive cell culture experience using adherent and suspension mammalian cell lines and primary cells.
Good understanding of cell characterisation and enumeration techniques.
Proficient in method development and validation skills with a keen interest in improving methodology/practices.
High level of organisation regarding sample preparation, data collection and data analysis.
Ability to work effectively in a team environment and work collaboratively in crossfunctional teams.

Desirable:

Proficient in the use of FCSExpress, FlowJo, CytExpert or Attune software for flow cytometry data analysis.
Prior experience of using the Attune, Cytoflex and BD FACS melody instrumentation.
Experience in using cell imaging techniques such as brightfield, widefield and confocal microscopy.
Prior experience within a regulated (cGxP) environment.
Prior experience of producing peer review publications and presenting (poster and presentation) work internally or externally.