- Applied Mathematics or Theoretical Physics
- Computational Biology or Bioinformatics
- Computer Science or Engineering
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Research Fellow
2 weeks ago
University of Birmingham Birmingham, United Kingdom**Position Details** · Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences · Location: University of Birmingham, Edgbaston, Birmingham UK · Full time starting salary is normally in the range £34,980 to £44,263, with potential progression once in post ...
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Associate Professor in Oral Biology
1 week ago
University of Birmingham Birmingham, United Kingdom**Position Details** · School of Dentistry, College of Medical and Dental Sciences · Location: University of Birmingham, Edgbaston, Birmingham UK · Full time starting salary is normally in the range £54,421 to £63,059 with potential progression once in post to £82,225 · Grade 9 · ...
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Aston University Birmingham, United Kingdom**Department**:College of Health and Life Sciences · **Contract Type**:Fixed Term · **Basis**:Full Time · **Closing Date**:30th June 2023 [23:59 GMT] · **Supervisory Team**:Principle Investigator: Dr Ewan Ross (College of Health and Life Sciences); Associate Supervisors: Dr Eirin ...
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Senior Digital Systems Trainer
1 day ago
The Royal Orthopaedic Hospital NHS Foundation Trust Northfield, United KingdomThe Royal Orthopaedic Hospital NHS Foundation Trust is the largest provider of elective orthopaedic surgery in the UK and provides both routine and specialist orthopaedic services. We are also a leading specialist centre for bone and soft tissue cancers and spinal surgery. · An e ...
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Biological Specimen Coordinator
1 week ago
The Institute of Cancer Research Sutton, United Kingdom**Key Information**: · **Salary**: · **Duration of Contract**: Maternity cover up to 12 months · **Hours per week***: 35 hours per week (Full Time) · **Closing Date***:21st November 2023 · **Job Details**: · Under the leadership of Professor Johann de Bono, we are seeking to appo ...
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Lead Biological Specimen Coordinator
3 weeks ago
The Royal Marsden NHS Foundation Trust Sutton, United KingdomThe post holder will lead the biological specimen team within the Haemato-Oncology Research Unit within the Royal Marsden NHS Foundation Trust and our Academic partner Institute of Cancer Research at both Chelsea and Sutton sites. The post holder will be responsible for ensuring ...
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Medical Laboratory Assistant
2 weeks ago
The Royal Marsden NHS Foundation Trust Sutton, United KingdomAn exciting opportunity has arisen for a Medical Laboratory Assistant (MLA), with good interpersonal skills and a committed team member to join the Clinical Genomics department. · Cytogenetics is part of the Clinical Genomics Department bringing together cytogenetics, translation ...
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Medical Laboratory Assistant
1 week ago
The Royal Marsden NHS Foundation Trust Sutton, United KingdomWe are seeking an enthusiastic and efficient medical laboratory assistant (MLA) to undertake essential technical duties for the histopathology laboratory. The laboratory is located in the Centre for Molecular Pathology, Sutton. · The post holder will be responsible for, assisting ...
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Scientific Officer
3 weeks ago
The Institute of Cancer Research Sutton, United Kingdom**Key Information**: · **Duration of Contract**: Fixed Term for 12 months · **Hours per week**: 14 hours per week (Part Time) · **Closing Date**: 21st August 2023** · **Job Details**: · Under the leadership of Dr Sunil Iyengar and Dr Dima El-Sharkawi, we are seeking to appoint a ...
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Licensed Animal Technician
1 week ago
S3 Science Sutton, United KingdomLicensed animal Technician · £ £32000 · We are proud to be working with our client, one of the world's most influential organisations that specialise in Cancer studies, on the hunt for a Licensed Animal Technician to join their team. Our client holds outstanding achievements in d ...
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Senior Scientific Officer
5 days ago
The Institute of Cancer Research Sutton, United Kingdom**Key Information**: · **Duration of Contract**: Fixed Term for 2 years, with the potential of extension · **Pay grade / staff group**: Analytical Scientist 2* or 3, Scientific Professional (Dependant on skills and experience) · **Hours per week**: 35 hours per week (Full Time) · ...
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Breast M3 Pathway Coordinator
2 days ago
The Royal Marsden NHS Foundation Trust Sutton, United KingdomWe have a new post commencing within the breast administrative team to work alongside existing staff. The role is develop safe pathways through diagnostics and recall arrangements. The post holder will be expected to liaise with clinical staff within breast and radiology services ...
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Dental Hygienist
2 weeks ago
High Town Dental Practice Bridgnorth, United KingdomThe position is fully private, for one day a week, initially on alternate Thursdays, with a view to add Fridays as well as the patient base grows. Patients are booked between 9am and 5pm (with an hour's lunch break). · **Responsibilities**: · - provide dental hygiene care to a wi ...
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Research Fellow
3 weeks ago
University of Birmingham Birmingham, United Kingdom Full time, Fixed-Term/ContractSalary: Full time starting salary is normally in the range £34,980 to £44,263 with potential progression once in post to £46,974. Grade 7 · Contract Type: Fixed Term contract up to January 2025 · The Rheumatology Research Group at the Institute of Inflammation and Ageing has an ...
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Research Fellow
2 weeks ago
University of Birmingham Birmingham, United Kingdom Full time, Fixed-Term/ContractA University of Birmingham funded post-doctoral research fellow position is available to work in the lab of Professor Jon Frampton in collaboration with Professor Amos Burke in the Institute for Cancer and Genomic Sciences at the University of Birmingham and with Professor Suzann ...
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The Institute of Cancer Research Sutton, United Kingdom Fixed termUnder the leadership of Prof Manuel-Salto-Tellez, we are seeking to appoint an Analytical Scientist in Digital Pathology and Tissue-based Artificial Intelligence to join the Integrated Pathology Unit to provide digital pathology (DP) and tissue-based artificial intelligence (AI) ...
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Licenced Animal Technician
1 week ago
S3 Science Sutton, United Kingdom Full timeLicensed animal Technician£ £32000We are proud to be working with our client, one of the world's most influential organisations that specialise in Cancer studies, on the hunt for a Licensed Animal Technician to join their team. Our client holds outstanding achievements in drug di ...
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Medical Laboratory Assistant
1 week ago
The Royal Marsden NHS Foundation Trust Sutton, United Kingdom Fixed-TermJob summary · We are seeking an enthusiastic and efficient medical laboratory assistant (MLA) to undertake essential technical duties for the histopathology laboratory. The laboratory is located in the Centre for Molecular Pathology, Sutton. · The post holder will be responsible ...
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Biomedical Scientist
1 week ago
The Royal Marsden NHS Foundation Trust Sutton, United Kingdom PermanentJob summary · Unlock an extraordinary career in the Cellular Therapy Laboratory Join our dynamic team at the heart of an experienced Haematology/Oncology stem cell transplant and cellular therapy programme. As an HTA licensed and JACIE accredited lab, we are dedicated to providi ...
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Bright Leaf Recruitment Tamworth, Staffordshire, United KingdomOur client in Tamworth have an opportunity for a consultant only veterinary surgeon to join them (surgery time available if desired). The successful candidate will be happy with managing their own caseload and ideally be happy to help new graduate veterinary surgeons as and when ...
PhD Studentship: Data-driven Probabilistic Modelling of Clonal Dynamics in Human Tissues and Cancers - Birmingham, United Kingdom - University of Birmingham
Description
Cancer is responsible for one in eight deaths, worldwide.Cancer initiation and development is driven by the accumulation of genetic mutations within cells that maintain and regenerate human tissues.
In the last decade, rapid advances in next-generation genome sequencing technologies have re-shaped the way we think about this mutational process.
Both cancer and tissues from healthy individuals are now known to be a mosaic of genetic "clones", each clone derived from a single common ancestor cell carrying a mutation similar to the way that mutation and selection govern the evolution of species.
Recently, scientists have employed mathematical modelling in combination with probabilistic inference to elucidate the dynamics of clonal evolution over the course of a human lifetime.
Such work has revealed an intricate balance of cellular interactions within human tissues, which can be perturbed by certain mutations to drive the emergence of cancer.
This project will develop and extend the above computational and mathematical analyses of clonal dynamics to different tissue and cancer types, including cancers of the colon, intestine and endocrine glands.
Depending on your interests and experiences, approaches used may include: 1) statistical analysis of "big data" coming from clinical genomics, 2) stochastic modelling of clonal dynamics, 3) Bayesian inference from experimental cell lineage tracing and imaging data.The project is therefore suitable for students with a background in (but not limited to):
While having a base in the School of Mathematics in Birmingham, you will join a research team that also includes world-leading clinicians and experimentalists, alongside established collaborations in Cambridge, London, Germany and Spain working together at the forefront of cancer research.
Funding notes:
A funded scholarship would be available for competitive candidates with a stipend at standard rates for 3.5 years. The project will be supervised by Dr David Tourigny ).
Apply online via the above
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