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Consultant Paediatric Haematologist
3 weeks ago
Nottingham University Hospitals NHS Trust Nottingham, United KingdomApplications are invited for a 10PA Substantive Consultant in Paediatric Haematology at Nottingham University Hospitals. The post will involve malignant, benign and laboratory haematology. An interest in either haemoglobinopathy or leukaemia will best complement the existing team ...
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Technical Sales Specialist
3 weeks ago
Anthony Nolan Nottingham, United KingdomWe're Anthony Nolan. We're here to uncover the answers inside us. Answers for people with blood cancer and blood disorders. Answers that will not only improve lives today but save them tomorrow. · By uniting people and science, we're growing our world-leading stem cell register, ...
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Process Biotechnologist
3 weeks ago
Sartorius Nottingham, United KingdomWe are looking for a Process Biotechnologist to join our production team in Nottingham. · Do you have production or manufacturing experience, with a good knowledge of mechanical assembly techniques? Are you a life science graduate who is looking to gain experience in a GMP enviro ...
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Consultant Paediatric Haematologist
3 weeks ago
Nottingham University Hospitals NHS Trust Nottingham, United KingdomConsultant · **Main area** · - Paediatric Haematology · **Grade** · - Consultant · **Contract** · - Permanent · **Hours** · - Full time - 10 sessions per week (1:6 on call comittment) · **Job ref** · **Site** · - Queens Medical Centre · **Town** · - Nottingham · **Salary** · - £9 ...
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Healthcare Science Associate
3 weeks ago
Nottingham University Hospitals NHS Trust Nottingham, United KingdomBand 4 · **Main area** · - Genomics · - **Grade** · - Band 4 · - **Contract** · - Fixed term: 12 months · - **Hours** · - Full time · - Part time · - Job share · - Flexible working · 37.5 hours per week · - **Job ref** · **Site** · - City Campus · - **Town** · - Nottingham · - ** ...
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Research Associate
3 weeks ago
University of Leicester Recruitment Team Leicester, United Kingdom**About the role**: · We are seeking a highly ambitious, flexible, and committed Post-doctoral Researcher to join Dr. Ning Wang's lab within the Leicester Cancer Research Centre, Department of Genetics and Genome Biology at the University of Leicester. · You will work on a projec ...
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Locum Consultant Paediatric Haematologist
1 week ago
Nottingham University Hospitals NHS Trust Nottingham, United KingdomApplications are invited for a 10PA Locum Consultant in Paediatric Haematology, or Oncologist/Paediatrician with an interest in Haematology at Nottingham University Hospitals. The post will involve malignant, benign and laboratory haematology. · Our East Midlands Children's and Y ...
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Research Fellow
1 week ago
Nottingham Trent University Nottingham, United Kingdom**Diverse community. Inclusive Research. Rewarding Careers.**: · **Doing things differently.**: · **Research Fellow in Neuroscience**: · £31,607-£36,371 (pro rata) · Fixed term 21 months · **About the Role**: · Modern day treatment of cancer has extended peoples lives. However, t ...
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Consultant Haematologist S/i in Haemostasis and
3 weeks ago
University Hospitals of Derby and Burton NHS Foundation Trust Derby, United KingdomAn exciting opportunity has arisen for a Consultant Haematologist with a specialist interest in Haemostasis and Thrombosis to join a friendly, enthusiastic team at UHDB as a new post, adding to an existing complement of 11 Haematologists. This is an 11-PA post and we have secured ...
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Clinical Fellow Thoracic Surgery
1 week ago
Nottingham University Hospitals NHS Trust Nottingham, United KingdomA whole-time clinical fellow (ST3+) in thoracic surgery is required at Nottingham City Hospital Campus to start in August 2023. Possession of MRCS (or equivalent) and previous experience in cardiothoracic surgery is essential. · The appointee will undertake routine out-patient cl ...
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Process Biotechnologist
2 weeks ago
Sartorius Nottingham, United KingdomWe are looking for a Process Biotechnologist in the dispensary and clean suites to join our team in Nottingham. · The site is expanding so it's a great time to join the team to further your career. · The team consists of 4 professionals, and we are looking forward to shaping the ...
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Clinical Fellow Thoracic Surgery
2 weeks ago
Nottingham University Hospitals NHS Trust Nottingham, United KingdomST3+ · **Main area** · - Thoracic Surgery · - **Grade** · - ST3+ · - **Contract** · - Fixed term: 12 months · - **Hours** · - Full time - 40 hours per week (40 hours per week) · - **Job ref** · **Site** · - City campus · - **Town** · - nottingham · - **Salary** · - £40,257- £51,0 ...
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Clinical Psychologist
1 week ago
Nottingham University Hospitals NHS Trust Nottingham, United KingdomBand 8b · **Main area** · - Clinical Psychology · - MESH · - **Grade** · - Band 8b · - **Contract** · - Permanent · - **Hours** · - Part time · - Job share · - Other · 15 hours per week (15 hours per week) · - **Job ref** · B**Site** · - Cross site · - **Town** · - Nottingham · - ...
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Consultant Medical Oncologist
2 weeks ago
University Hospitals of Derby and Burton NHS Foundation Trust Derby, United Kingdom PermanentJob summary · University Hospitals of Derby & Burton are seeking to recruit a Consultant Medical Oncologist, who together with 17 other Consultant Oncologists will provide a comprehensive service for the people of Southern Derbyshire and East Staffordshire. · We are looking for ...
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Research Scientist Animal Technician
2 weeks ago
hr-inspire Ltd Loughborough, United Kingdom**Research Scientist Animal Technician**: · - Job Reference: · - Date Posted: 31 August 2023 · - Recruiter: hr-inspire Ltd · - Location: Loughborough, Leicestershire · - Salary: On Application · - Sector: Business development, Creative & design, Technology · - Job Type: Permanen ...
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Life Science Sales Specialist
2 weeks ago
Avantor Leicestershire, United KingdomJob Summary · This role will be a full-time, remote position, covering WA, LL, CW, ST, SY, SA, TA, EX, DT, TQ, GL postcodes. You will be responsible for maintaining relationships with accounts by visiting customer sites within assigned territory. · The team · Avantor's Life Scien ...
PhD studentship: Development and application of recombinant antibodies to map pathology-related changes in glycosaminoglycans on breast cancer cells - Nottingham, United Kingdom - University of Nottingham
Description
Project title: Development and application of recombinant antibodies to map pathology-related changes in glycosaminoglycans on breast cancer cells
Principal supervisor : Professor Kevin Gough
Other supervisors: Professor Cathy Merry, Dr Cinzia Allegrucci, Dr Jennifer Ashworth, Dr Kieran Pitchers
Background: The School of Veterinary Medicine and Science undertakes a wide range of research from fundamental biology to population studies. The research undertaken at the School is integrated into the University structure with established world class research in biomedical sciences.
Project description: The PhD student will join an extensive team of scientists delivering a BBSRC strategic Longer and Larger project, . The team includes research groups from The University of Nottingham, Liverpool University, Manchester University, and the Francis Crick Institute, alongside international (USA and Denmark) and commercial (InterReality Labs) partners. Glycosaminoglycans (GAGs) are a class of biomolecules that decorate the surface of virtually all cells in the body. They play critical roles in a multitude of biological processes, including cell signalling and development, and are known to be dysregulated in disease, including cancers. Despite their ubiquity and clear importance, we lack a thorough understanding of how the molecular structure of a particular GAG links to its biological function. To compound this problem, there is currently a lack of tools with which to detect and characterise GAGs in tissues and on cells.
This studentship will aim to isolate a range of recombinant antibodies that bind to GAGs, producing highly specific probes. The post will use the very latest developments in antibody phage display technology, coupling the binding of vast antibody-phage libraries containing billions of potential binders with the screening power of next generation sequencing (a process termed next generation phage display, NGPD). The studentship will apply NGPD to target cell surface GAGs from breast cancer cell populations, identify specific binders, clone and express binders and finally, characterise binding against breast cancer cell populations and defined GAG structures. You will be embedded within a highly active phage-display group at the University of Nottingham and have the opportunity to interact with the whole Glycoweb team, visit collaborator's labs and extend your research knowledge and collaborator network.
Further information and Application
Applicants should have a minimum of a 2.1 undergraduate biological science degree or a minimum of a 2.2 degree and a Master's degree in a related subject.
