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Macclesfield

    LC-MS Scientist - Macclesfield, Cheshire, United Kingdom - CK Group- Science, Clinical and Technical

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    Permanent, Full time
    Description
    CK Group are recruiting for a lab-based LC-MS Scientist to join a precision medicine company based near Manchester.

    Company:


    Our client is developing next-generation diagnostic tests to help clinicians prescribe the right drug, for the right patient, at the right time.

    They are developing LC-MS proteomic biomarker discovery platforms and clinical assays to predict drug response in a clinical setting.

    The Role:

    Support the development of biomarker discovery platforms and resulting clinical assays.
    Be involved in a variety of projects that aim to expand the portfolio of proteomic assays
    Sits within the LC-MS/MS technical operations team and involves operation of LC-MS/MS systems and method development

    Your Background:

    Ph.
    D. in proteomics or protein biochemistry applied to the investigation of mammalian cell biology

    Expertise in LC-MS/MS proteomics - hands-on experience running/operating high-end LC-MS/MS systems (including hands-on experience calibrating the MS systems, basic maintenance of LC-MS/MS, renewing buffers, running QCs, interpreting data, and reporting QC outputs).

    Experienced in preparing samples using proteomic workflows for LC-MS/MS analysis.
    Experience working with multiple sample types (e.g. cell lines, blood, solid tissue).
    Knowledge and understanding of fundamental principles of biochemical and molecular biological systems.

    Desirable:

    Experience analysing large sample sets, across multiple batches.
    Experience using software for the identification, characterisation and quantification of peptides and proteins from LC-MS/MS raw data.
    Expertise in the utilisation of LC-MS/MS proteomic technologies for the identification and validation of clinical biomarkers.
    Experience in automation of sample preparation workflows using liquid handlers.
    Experience building targeted (e.g., PRM/SRM) or untargeted (e.g., DDA/DIA) methods for proteomics.

    Apply:

    It is essential that applicants hold entitlement to work in the UK. Please quote job reference T56527 in all correspondence

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