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    Postdoctoral Research Scientist - Norwich, United Kingdom - Earlham Institute

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    Description

    The role:

    The post holder will lead on the development and testing to applications to identify noncoding functional elements based on integration of multi-omic data (genome, transcriptome, epigenome) and integrate this novel information in the development of tissue / condition specific regulatory network, with the aim of prioritising variants occurring within those regions based on their predicted impact. They will also lead on the analysis, preparation, and submission of the associated manuscripts.

    The successful candidate will develop computational pipelines centered on machine learning applications such as convolutional neural network to reproducibly handle multi-omic data (genome, transcriptome, epigenome) to enable functional sequence annotation, network reconstruction, and the interpretation of the implication of genetic variation within those disorders.

    The post holder will have access to cutting-edge high performance computing facilities and expertise. They will join an active community of experimental and computational biologists working on a wide range of genomics analyses. They will also have the opportunity to contribute to other projects at EI.

    The ideal candidate:

    The successful applicant will have a PhD in bioinformatics, computational genomics or a related subject.

    They will have significant experience working with genomic/epigenomic/transcriptomic data, and experience with machine learning applications in genomics investigations. The candidate should have a demonstrable working knowledge of programming languages such as Python, Perl, or R.

    Additional information:

    Salary on appointment will be within the range £35,300 to £43,750 per annum depending on qualifications and experience. This is a full-time post until 31 December 2027, with a possibility of a 6-month extension.

    This role meets the criteria for a visa application, and we encourage all qualified candidates to apply. Please contact the Human Resources Team if you have any questions regarding your application or visa options.

    As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.

    The closing date for applications will be 11 June 2024.


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