Postdoctoral Fellow - Hinxton, United Kingdom - Wellcome Sanger Institute

Wellcome Sanger Institute
Wellcome Sanger Institute
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Hinxton, United Kingdom

1 week ago

Tom O´Connor

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Tom O´Connor

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Description

Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity's greatest challenges.


About the Role:
We have an opportunity for a

Postdoctoral Fellow

to join our

Genomics of Inflammation and Immunity group

at the Wellcome Sanger Institute (WSI), headed by Dr. Carl Anderson for a 3 year fixed term contract.


About Us:

You will be responsible for:


This role presents an exciting opportunity for you to use your immunology or computational genomics expertise to lead a project aimed at elucidating the cellular and molecular mechanisms underpinning IBD susceptibility, progression and drug response.

As part of the nationwide

IBD-Response study

, we are generating single-cell RNA sequencing data from blood samples ascertained from over 1,300 IBD patients before and after the initiation of biologic therapy. Gut biopsies from approximately 500 patients will also undergo single-cell RNA sequencing, and genetic data is available for all sample donors. Using these data, you will lead a series of analyses to identify biomarkers of treatment of response and map genetic variants associated with gene regulation in disease-relevant cell types. You will form part of a collaborative team of experts in genetics, genomics, immunology and gastroenterology to draw causal insights into disease pathogenesis and drug response.


About you:
Open Targets


partners (Bristol Myers Squibb, GSK, Pfizer, and Sanofi) and this is an opportunity for you to make a personal contribution to genomic research at the interface of academia and the pharmaceutical industry.


Essential Skills:

  • Ability to work with others in a collegiate and collaborative environment.
  • Motivation and ambition to make a personal contribution to genomic research.
  • Experience leading large-scale data science projects.
  • Experience with analysis of genotype, sequence or functional genomic data.
  • Experience with computer programming & scripting.
  • Experience and enjoyment of scientific writing.
  • Attention to detail and a drive for rigour.
  • Demonstrates inclusivity and respect for all.

Other Information:

Salary per annum:
£34,819-£43,600

Closing Date: 8th January 2023

Working at Wellcome Sanger


Our flexible-hybrid working environment means you can focus on being productive and part of the team while enjoying the benefits of working remotely and from the Genome Campus when you are in the office.


We aim to attract, recruit, retain and develop talent from the widest possible talent pool, thereby gaining insight and access to different markets to generate a greater impact on the world.

We have a

supportive culture


with the following staff networks, LGBTQ+, Parents and Carers and Race Equity to bring people together to share experiences, offer specific support and development opportunities and raise awareness.

The networks are also a place for allies to provide support to others.


We want our people to be whoever they want to be because we believe people who bring their best selves to work, do their best work.

That's why we're committed to creating a truly inclusive culture at Sanger Institute.

We will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.

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