- Leading the purification development of biological components, such as protein nanopores, peptides and sequencing adapters.
- Improving the design of the biological components to increase sequencing accuracy and throughput.
- Process development and scale up.
- Bio-conjugation and chemical biology.
- High-resolution characterisation of the biological components.
- Technology transfer to internal and external manufacturing teams.
- Managing multiple projects in a very fast paced and agile environment.
- Working and communicating effectively with other groups in R&D and Production.
- 3+ years of relevant industry experience.
- PhD level in a biochemistry, chemistry, or related subject is advantageous.
- Significant experience in biomolecule chromatography, especially with HPLC.
- Good problem-solving and analytical skills and strong attention to detail.
- Strong communication skills and a desire to learn and build on the role. Experience in the following areas would be advantageous:
- In-depth understanding of chromatographic equipment.
- Scale up and process development.
- Significant experience with biological characterisation, especially via HPLC.
- Experience managing a group of scientists.
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Development Scientist - Oxford, United Kingdom - Oxford Nanopore Technologies
Description
Oxford Nanopore Technologies is headquartered at the Oxford Science Park outside Oxford, UK, with satellite offices and commercial presence in many global locations across the US, APAC and Europe. Oxford Nanopore employs from multiple subject areas including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialisation. The management team, led by CEO Dr Gordon Sanghera, has a track record of delivering disruptive technologies to the market.
Oxford Nanopore's sequencing platform is the only technology that offers real-time analysis (for rapid insights), in fully scalable formats from pocket to population scale, that can analyse native DNA or RNA and sequence any length of fragment to achieve short to ultra-long read lengths.
Our goal is to enable the analysis of any living thing, by anyone, anywhere. We offer real-time nanopore-based DNA/RNA sequencing technology: accessible, easy to use and fully scalable for any requirement.
We are looking for a motivated individual with good laboratory-based skills to join our Chemistry Development team.
The Details...
In this exciting and challenging role the candidate will assist in taking many of the most challenging biological complexes, central to the sequencing technology, from development through to product stage.
Working closely with other members of the Chemistry Development team, the candidate will use high-resolution HPLC purification and analytical techniques, in combination with a broad knowledge of chemistry and biochemistry, to achieve this goal. In so doing they will improve the performance, add consistency, and scale up the next generation of sequencing components.
The candidate will take on a technical leadership role and play a collaborative role in the decision making of key objectives that influence future projects, the team, and the company.
The role will involve:What We're Looking For...
This role will suit someone willing to learn, who is motivated to achieve results and performs well under pressure.
We offer outstanding benefits to include an attractive bonus, generous pension contributions, private healthcare and an excellent starting salary. Based within beautiful, landscaped surroundings with tree-lined walks, water features and a lake, all of which make for a wonderful working environment.
If you are looking to utilise your skills to really make a difference to humankind, then consider joining our team and apply today
Development Scientist professionals in Oxford
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Alfredo Maria Gravagnuolo
Principal Scientist at VATIC HEALTH LIMITED