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    Engineering Manager - Belfast, United Kingdom - HIRANI

    HIRANI
    HIRANI Belfast, United Kingdom

    1 week ago

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    Description

    Reporting to the Operations Manager, the role of Antibody Engineering Manager will be responsible for all aspects of protein engineering, particularly monoclonal antibody drugs.

    This will include multi-specific antibody design, affinity maturation, protein-protein docking, developability analysis, humanization and antigen design. The Antibody Engineering Manager will manage a team of scientists while acting as a liaison with other business units.
    Responsibility for planning, implementation and management of projects (including liaising with clients on a weekly basis).
    Share and discuss data with management to ensure production demands are met within agreed timelines.

    Responsible for the line management and development of other scientific staff within Fusion (support and supervision, training, staff appraisals etc).

    Responsible for addressing all aspects of Antibody Engineering within the company including Antibody Humanization, Antibody Developability, Multispecific Antibody Reformatting and Antibody Affinity Maturation (RAMP).

    Work cohesively with the R&D team to develop new innovative Antibody Engineering technology.

    Responsible for introducing state of the art technology into the antibody engineering workflow including machine learning for drug discovery and optimization.

    Keep abreast of advancements within their area of expertise.
    Ensure proprietary and external software in the Antibody Engineering department is up to date and functioning optimally.
    Ensure that all duties are performed in accordance with organisational standards, policies and procedures.
    PhD in Bioinformatics, Computational Chemistry/Biology or related field, or MSc with 1+ years of industry experience.
    Key skills of the post holder include project management and excellent communication
    Experience with MS office applications.
    Industrial experience in computational biology, immuno-informatics, protein engineering, or structural biology.
    Familiar with machine learning methods used in protein/antibody engineering.
    Software engineering skills, especially with the Python programming language.
    Familiar with NGS repertoire analysis.

    Have the ability to mentor more junior members of the team and also be able to share your specialist knowledge with those you collaborate with.

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