- Participates in the rota for the routine aseptic production of radiopharmaceuticals within the Radiopharmacy Unit.
- The post-holder will routinely undertake early morning shift work am start).
- Accurately and safely aseptically manufacture routine radiopharmaceuticals for administration to patients within the Trust and external hospitals in accordance with Radiopharmacy procedures and Local Rules for Radiation Protection and ensure that they are ready at the requested time.
- To ensure that preparation of prescribed radioactive medicines is undertaken in accordance with relevant legislation e.g. EC Good Manufacturing Practice (GMP).
- Participation in the preparation of non-routine radiopharmaceuticals and non-radioactive pharmaceuticals when requested to do so by the Head of Radiopharmacy, Radiopharmacy Production Manager and other staff.
- To conduct radiopharmaceutical production work with due speed and efficiency, having regard to the need for a high degree of precision, making appropriate allowances for radioactive decay.
- To participate in the preparation of batches of long-lived radiopharmaceuticals when requested to do so by Senior Radiopharmacy staff.
- To receive radioactive stock and other materials for the Radiopharmacy Unit. Unpack and store in accordance with procedures.
- Act to resolve any problems that arise with the radiopharmaceutical production runs.
- To participate in the highly specialised blood radiolabelling service when requested to do so by the Radiopharmacy Production Manager in accordance with the standards set out in the procedures and local rules and to ensure that they are ready at the requested time to be administered to the patient.
- Participate in the routine quality control checks on radiopharmaceuticals according to the procedures are laid down, ensuring that these checks are recorded accurately and that any failure(s) is reported to the Senior Radiopharmacy Staff and relevant Nuclear Medicine Consultant for further action.
- Prepare samples for end of the session media fill tests as specified in the procedures.
- To undertake and or supervise the routine pharmaceutical environmental monitoring in accordance with the procedures.
- Carry out calibration and appropriate tests on key equipment and facilities and to inform Senior Radiopharmacy staff of any problems or unusual occurrences immediately when they occur.
- To assist in performing highly specialised techniques for the quality control of radiopharmaceuticals.
- To co-ordinate the day-to-day technical aspects involved in the manufacture of radiopharmaceuticals.
- To plan and manage radiopharmaceutical production runs to ensure that all requested items can be made with the available radioactive solution. This may require re-elution of the radioactive generator. If demand exceeds this, to liaise with customers to reduce the number of requested products. This also involves accurately transcribing prescription
details to generate worksheets and labels for the manufacture of radioactive medicines in line with National, Regional and local guidance. - Responsible for day to day supervision and training of the Senior Assistant Technical officer undertaking duties in the Radiopharmacy Unit and ensuring these duties are carried out during their absence.
- To participate in development and review of Policies and Standard Operating Procedures as required.
- Assist in the implementation of changes in accordance with EU GMP so that it can be demonstrated that all rotational senior clinical technologists and junior staff are trained where appropriate. The post-holder has a responsibility to demonstrate an awareness of changes.
- To assist the Senior Radiopharmacy staff to resolve any problems that may arise with the operation of the AHU plant and any equipment and liaise with the Estates Department to arrange maintenance.
- To participate in pharmaceutical quality audits required under EU GMP and gather relevant information.
- To participate in undertaking pharmaceutical validation work.
- Review current practices and policies and propose changes where benefit to customers, other healthcare professionals and patients may result.
- To liaise with professional and technical staff within the Trust and other departments to assure a quality service and to resolve problems.
- Perform any other duties consistent with grade which may reasonably be required by the Head of Radiopharmacy, Radiopharmacy Production Manager and Systems Quality Manager.
- To participate in research and development projects as requested by the Head of Radiopharmacy.
- To participate in clinical trials involving the preparation of radioactive medicines.
- To participate in the packaging of radioactive materials and preparation of legal documents for the transport of radioactive materials by road.
- To take responsibility for conforming to the local Rules for Radiation Protection, including decontamination procedures.
- Dispose of used and expired radiopharmaceuticals and other radioactive and clinical waste (when required) with due regards to local radioactive waste disposal procedures.
- To participate in radioactive contamination monitoring within the Radiopharmacy Unit in accordance with the procedures and Local Rules and record results of such measurements.
- To assist the Radiopharmacy Production Manager in maintaining the stock control system for consumable items used in the preparation and quality control of radiopharmaceuticals in the Radiopharmacy Unit.
- To complete all necessary paperwork, labels and other documentation required for the preparation and quality control of radiopharmaceuticals in accordance with EU GMP.
- Maintain records for the receipt and disposal of radioisotopes in accordance with Radiation Protection requirements.
- Responsible for maintaining own competency to practice through CPD activities undertaking on-the-job and other training and maintain a portfolio that reflects personal development.
- As part of professional development and maintaining competency to practice, the post holder is expected to attend courses and meetings relevant to Radiopharmacy.
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