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Scientist - Preclinical Biology, Autoimmunity - 12 months FTC - Abingdon, Oxfordshire, United Kingdom - Immunocore
Description
Job Details: Scientist – Preclinical Biology, Autoimmunity - 12 months FTC
Full details of the job.
Vacancy Name
Vacancy Name Scientist – Preclinical Biology, Autoimmunity - 12 months FTC
Vacancy No
Vacancy No VN172
Employment Type
Employment Type Fixed Term
Location of role
Location of role Abingdon
About the Company
About the Company Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry's most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.
Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. We strive to create a diverse and inclusive workplace, while seeking talented individuals to work with us across the many functions that will allow us to deliver new medicines to transform the lives of patients. You will work with outstanding people who together pioneer the research, development and commercialization of bi-specific TCR therapies. We aim to create an environment where individual contributions and initiatives can be maximized, while fostering a culture of collaboration, based on respect and integrity. We want each individual employee to own their career, as part of high-performing teams, and in the context of on-the-job and formal continuous development and training, as well as constructive feedback. We always strive to identify ways to improve what we do and how we do it, by asking questions, voicing opinions, exploring various approaches and staying connected with healthcare professionals, patients, academia and other key partners.Key Responsibilities
Key Responsibilities Our Pipeline Biology department has an immediate opening for a Scientist to join the Preclinical Autoimmunity team for a 12 months fixed term contract. The post holder should have proven practical experience in immunological assays, with demonstrable skills in problem-solving, the ability to work collaboratively, and enthusiasm to learn new skills and contribute to drug discovery. This is an exciting opportunity for a passionate and motivated scientist to become part of a high-performing and dynamic team.
MAIN PURPOSE OF JOB To lead, conduct and design experimental investigations, with appropriate guidance from colleagues and managers, enabling the advancement of the Company autoimmunity preclinical pipeline, and associated technology capabilities. KEY RESPONSIBILITIES• Conduct and analyse cell biology assays supporting ImmTAAI (Immune Modulating Monoclonal TCRs Against Autoimmune Disease) screening and selection and/or preparation of preclinical packages, following set protocols and/or supervisor's guidance in accordance with set timelines.
• Analyse and interpret data, communicating results and next steps to multidisciplinary programme teams, via written reports and oral presentations at meetings
• Maintain and further develop technical knowledge in relevant fields through self-study, observation and training courses.
• Execute lab work for preclinical projects assigned by manager/supervisor and contribute to defining questions and suggesting lines of investigation within these projects.
• Design and analyse experiments to answer specific biological questions and contribute to interpretation of the data.
• Contribute to preclinical study report writing.
• Provide support to other scientists within Pipeline Biology when required, and to the operational running and maintenance of Cell Biology laboratories and equipment, strictly adhering to the Company's Health and Safety policies. EXPERIENCE AND KNOWLEDGE Essential
• Worked in a bench-based laboratory with proficiency in cellular and immunological based techniques including cell culture of immortalised cell lines and primary human cells, T cell function assays (measuring proliferation and cytokines), flow cytometry, ELISA, reporter based assays
• Recorded and analysed results in a concise and timely way, and in compliance with agreed protocols
• Able to meaningfully lead and stimulate scientific team discussions, especially with regards to the broader interpretation of their own data
• Presented results and scientific practices with excellent communication and organisational skills
• Worked and contributed actively within a diverse team environment
• Proven enthusiasm for learning and progressing career development Desirable
• Pharma or biotech laboratory experience
• Theoretical knowledge and understanding of immunology and autoimmune diseases
• Experience in study report writing
• Experience with any of the following laboratory techniques or platforms: ELISA, MSD, Flow cytometry, InCucyte, xCelligence or high content imagers, liquid dispensing robotics
• Experience in mentoring others
• Publication in peer-reviewed journals EDUCATION & QUALIFICATIONS Essential: BSc. or MSc. in cell biology, immunology, molecular biology, biochemistry, or related discipline plus post graduate work experience in industry or academia. Desirable: PhD in a related discipline with some industry work experience. #J-18808-Ljbffr
