-
Research Scientist
1 week ago
The Earlham Institute Norwich, Norfolk, United KingdomAs part of the Cellular Genomics and Decoding Biodiversity Institute Strategic Programmes, the role will engage with primary research. The post holder will lead on the production and analyses of genomic, transcriptomic, and epigenomic data encompassing population, and single cell ...
-
Research Scientist
2 days ago
Earlham Institute Norwich, Norfolk, United KingdomApplications are invited for a Postdoctoral Research Scientist to join the Research Faculty Department at the Earlham Institute, based in Norwich, UK. · In humans, over 90% of the variants associated with traits are found within noncoding regions of the genomes, either within ge ...
-
Research Scientist
6 days ago
Earlham Institute (EI) Norwich, Norfolk, United KingdomApplications are invited for a Postdoctoral Research Scientist to join the Laboratory of Dr Wilfried Haerty in the Research Faculty of the Earlham Institute, based in Norwich, UK. · Climate change imposes unprecedented challenges to organisms, both through the rapid change of th ...
-
Research Scientist
1 week ago
Quadram Institute Norwich, United Kingdom 18 months, Full timeResearch Scientist · Applications Close: 23 November 2023 · Salary: £35,300 to £43,750 per annum depending on qualifications and experience · Contract Length: 18 months, full-time · We're looking for a Research Scientist to join the Laboratory of Fred Warren in our Food, Microbe ...
-
Postdoctoral Research Scientist
2 days ago
Earlham Institute Norwich, Norfolk, United KingdomApplications are invited for a Postdoctoral Research Scientist to join the Research Faculty Department at the Earlham Institute, based in Norwich, UK. · Background: · In humans, over 90% of the variants associated with traits are found within noncoding regions of the genomes, e ...
-
Postdoctoral Research Scientist
3 days ago
Earlham Institute (EI) Norwich, Norfolk, United KingdomApplications are invited for a Postdoctoral Research Scientist to join the Laboratory of Dr Wilfried Haerty in the Research Faculty of the Earlham Institute, based in Norwich, UK. · Background: · Climate change imposes unprecedented challenges to organisms, both through the rap ...
-
Postdoctoral Research Scientist
2 weeks ago
Earlham Institute Norwich, United Kingdom Full time, Fixed-Term/ContractApplications are invited for a Postdoctoral Research Scientist to join the Laboratory of Dr Wilfried Haerty in the Research Faculty of the Earlham Institute, based in Norwich, UK. · Background: · Climate change imposes unprecedented challenges to organisms, both through the rapid ...
-
Postdoctoral Research Scientist
1 week ago
Earlham Institute Norwich, United Kingdom Full timeApplications are invited for a Postdoctoral Research Scientist to join the Laboratory of Dr Paul Kroon in the Food, Microbiome and Health programme at Quadram Institute Bioscience (QIB), based in Norwich, UK. · Background: · The Postdoctoral Researcher will work on the BBSRC-fund ...
-
Postdoctoral Research Scientist
5 days ago
NBI Partnership Norwich, United KingdomJob Description · Main Purpose of the Job · As part of the Cellular Genomics and Decoding Biodiversity Institute Strategic Programmes, the role will engage with primary research. The post holder will be working closely with external partners focusing on investigating the genomi ...
-
Postdoctoral Research Scientist
1 week ago
Earlham Institute Norwich, United KingdomThe role: · The post holder will lead on the development and testing to applications to identify noncoding functional elements based on integration of multi-omic data (genome, transcriptome, epigenome) and integrate this novel information in the development of tissue / condition ...
-
Data Scientist Research
1 week ago
Centre for Environment, Fisheries and Aquaculture Science Lowestoft, Suffolk, United KingdomOrganisation Centre for Environment, Fisheries and Aquaculture Science Locations Lowestoft, UK · Application Deadline 39 days remaining Salary £ 51,685 - £58,105 The Centre for Environment, Fisheries and Aquaculture Science (Cefas) is a world leader in marine science and technol ...
-
Research Group Leaders
3 days ago
Quadram Institute Norwich, United KingdomDelivering to our mission is the responsibility of our research group leaders, recognised experts in their fields who manage interdisciplinary research groups. As well as carrying out excellent research, groups host PhD students, reflecting the importance the Quadram Institute pl ...
-
Group Leader
3 days ago
Quadram Institute Norwich, United KingdomApplications Close: 17 May 2024 · **Salary**: Competitive · Contract Length: Indefinite · **Full or Part Time** · **We are looking for** **a dynamic, proactive individual to lead a research programme contributing to our goals of reducing foodborne illness through improved food sa ...
-
Consultant Virologist
6 days ago
Norfolk and Norwich University Hospitals NHS Foundation Trust Norwich, United KingdomWe are excited to offer this rare opportunity for the post of Consultant Medical Virologist in the Eastern Pathology Alliance (EPA) department of Medical Microbiology based at the Norfolk and Norwich University Hospital and the Norwich Research Park. · 1. Provide a comprehensive ...
-
Sample Collector
1 week ago
Synlab Norwich, United KingdomForming part of the SYNLAB Group, Lextox are a UKAS accredited laboratory based in Cardiff. Lextox provide drug, alcohol and DNA testing services for family law cases and childcare proceedings. SYNLAB in the UK is a trusted expert in clinical laboratory and medical diagnostic ser ...
-
Sample Collector
1 week ago
Lextox Norwich, United KingdomForming part of the SYNLAB Group, Lextox are a UKAS accredited laboratory based in Cardiff. Lextox provide drug, alcohol and DNA testing services for family law cases and childcare proceedings. SYNLAB in the UK is a trusted expert in clinical laboratory and medical diagnostic ser ...
-
Sample Collector
1 week ago
Lextox Norwich, United KingdomForming part of the SYNLAB Group, Lextox are a UKAS accredited laboratory based in Cardiff. Lextox provide drug, alcohol and DNA testing services for family law cases and childcare proceedings. SYNLAB in the UK is a trusted expert in clinical laboratory and medical diagnostic ser ...
-
Senior Fisheries Biologist
2 days ago
Centre for Environment, Fisheries and Aquaculture Science Lowestoft, United Kingdom**Details**: · **Reference number**: · **Salary**: · - £37,295 - £41,425- A Civil Service Pension with an average employer contribution of 27%**Job grade**: · - Senior Executive Officer**Contract type**: · - Permanent**Type of role**: · - Science**Working pattern**: · - Flexible ...
-
Plankton Ecologist
6 days ago
Centre for Environment, Fisheries and Aquaculture Science Lowestoft, United Kingdom**Details**: · **Reference number**: · **Salary**: · - £31,825 - £34,285- A Civil Service Pension with an average employer contribution of 27%**Job grade**: · - Higher Executive Officer**Contract type**: · - Permanent**Business area**: · - CEFAS - Science**Type of role**: · - Sci ...
-
Cleaner
5 hours ago
Norwich Bioscience Institute (NBI) Norwich, United Kingdom ContractCleaner · TheNorwich Bioscience Institutes Partnership (NBIP) has an excitingopportunity for three Cleaners to join their busy Facilitiesdepartment. · Background: · TheNorwich Bioscience Institutes are a cluster of internationallyrenowned research organisations, working to tackle ...
Postdoctoral Research Scientist - Norwich, United Kingdom - Earlham Institute
Description
Applications are invited for a Postdoctoral Research Scientist to join the Research Faculty Department at the Earlham Institute, based in Norwich, UK.
Background:
In humans, over 90% of the variants associated with traits are found within noncoding regions of the genomes, either within genes' introns, untranslated regions, promoters, or within intergenic regulatory regions such as enhancers. Identifying those functional noncoding sequences and being able to predict the impact of variation within those regions has significant implications. As such, depending on the genetic disorder, between 30% and 70% of the patients do not receive a genetic diagnosis as the likely causative variants fall outside coding sequences.
The recently funded Horizon NextGen consortium encompassing 21 organisations across Europe aiming at developing federated approaches to enable the integration of multimodal and multiomic resources for applications in the areas of cardiovascular medicine. As part of this highly collaborative project bringing together computer scientists, data scientists, bioinformaticians, clinicians across academia and industry, we are seeking an enthusiastic and ambitious postdoctoral computational biologist to undertake computational analysis of the functional implications of variation within noncoding functional sequences in relation to cardiovascular disorders.
As part of the EU Horizon / Innovate UK funded project "Next Generation Tools for Genome-Centric Multimodal Data Integration in Personalised Cardiovascular Medicine", the role will engage with primary research. The postholder will work closely with external partners and members of the EU consortium, and will focus on developing machine learning applications to investigate the implications of genetic variation within noncoding functional elements in relation to cardiovascular disorders.
The role:
The postholder will lead on the development and testing to applications to identify noncoding functional elements based on integration of multi-omic data (genome, transcriptome, epigenome) and integrate this novel information in the development of tissue / condition specific regulatory network, with the aim of prioritising variants occurring within those regions based on their predicted impact. They will also lead on the analysis, preparation, and submission of the associated manuscripts.
The successful candidate will develop computational pipelines centered on machine learning applications such as convolutional neural network to reproducibly handle multi-omic data (genome, transcriptome, epigenome) to enable functional sequence annotation, network reconstruction, and the interpretation of the implication of genetic variation within those disorders.
The postholder will have access to cutting-edge high performance computing facilities and expertise. They will join an active community of experimental and computational biologists working on a wide range of genomics analyses. They will also have the opportunity to contribute to other projects at EI.
The ideal candidate:
The successful applicant will have a PhD in bioinformatics, computational genomics or a related subject. They will have significant experience working with genomic/epigenomic/transcriptomic data, and experience with machine learning applications in genomics investigations. The candidate should have a demonstrable working knowledge of programming languages such as Python, Perl, or R.
Additional information:
Salary on appointment will be within the range £35,300 to £43,750 per annum depending on qualifications and experience. This is a full-time post until 31 December 2027, with a possibility of a 6-month extension.
For further information and details of how to apply, please visit our website or contact the Human Resources team on or quoting reference This role meets the criteria for a visa application, and we encourage all qualified candidates to apply. Please contact the Human Resources Team if you have any questions regarding your application or visa options.
As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.
The closing date for applications will be 11 June 2024.
&v=024){kind=logo}
