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    Scientist - Protein Expression (CHO/HEK cells) - london, United Kingdom - BioTalent

    Default job background
    Pharmaceutical / Bio-tech
    Description

    Biotalent is collaborating with a leading biotechnology company based in London focused on developing biologics to tackle cancer diseases.

    This is a fantastic opportunity for a scientist with strong background working with CHO/HEK cell lines within R&D.

    Key Responsibilities:

    • Design and engineer plasmids for the expression of various recombinant proteins, including antibodies and antigens, in CHO/HEK cell lines.
    • Develop stable CHO cell lines to scale up antibody production to multi-gram quantities.
    • Optimise antibody production using fed-batch processes in bioreactors, ensuring high titer and quality.
    • Innovate within the protein expression domain, staying abreast of and implementing cutting-edge technologies.

    Candidate Expectations:

    • A solid foundation in cell and molecular biology. MSc or PhD.
    • Proven experience in transient protein expression in CHO/HEK293 cells and in scaling up antibody production.
    • Familiarity with bioreactor fermentation and depth filtration processes.


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