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    Process Development Chemist - United Kingdom - Scientific Update Ltd.

    Scientific Update Ltd.
    Scientific Update Ltd. United Kingdom

    1 week ago

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    Description

    Process Development Chemist (all levels)

    Sai Life Sciences Ltd

    permanent

    Role

    Process Development Chemist (All levels)

    Location

    Job Type

    Permanent

    Date posted

    9 th April 2024

    ASAP

    TheCompany

    Sai Life Sciences is a leading global Contract Research & Development and Manufacturing Organisation (CDMO) that provides integrated drug substance services to the biotech and pharmaceutical industries. With expanded process development labs in Manchester, UK & Hyderabad, India, and increased commercial manufacturing capacity in Bidar, India, Sai is working with 17 of the top 20 pharma companies globally, as well as many leading smaller biotechs. We work with our clients to accelerate the discovery, development and manufacture of complex small molecules for a healthier tomorrow. With more than 3000 staff globally and ambitious growth plans, our vision is to support our global innovator partners to bring 25 new medicines to life by 2025.

    In 2019 the company began an organisation-wide initiative to significantly expand and upgrade its R&D and manufacturing facilities, deepen scientific & technological capabilities, strengthen automation and data systems, and above all raise the bar for safety, quality and customer focus. Guided by the insights and feedback from its customers, it committed to investing over US$150M between 2019 and 2023. Part of this investment in 2020 were the new state of the art laboratories in our centre of excellence for process chemistry and analytical development at the Alderley Park Science Park, situated on the outskirts of Manchester. Our overall team currently consists of >60 multi-disciplinary scientists (chemists, analysts and engineers).

    Non-GMP manufacture of kg quantities of intermediates and APIs is currently possible within our bespoke Scale-up laboratory facility and a new GMP Kilo-lab facility was brought online in 2023 capable of kg quantities of GMP API suitable for early phase clinical studies. Developed processes are frequently transferred to Sai's manufacturing sites in India for further scale-up when required.

    The role will be based in Alderley Park, Cheshire, UK and will require right to work in the UK. Occasional travel, domestic and international to India may be required.

    The Role

    · You will join a team that identifies, develops and optimises synthetic routes and processes to APIs, supporting both early and late phase development.

    · The successful candidate will either have a strong technical grounding in Organic Chemistry with experience in a relevant industry or will be someone who has recently completed (or who will complete during 2024) a BSc, MSc, PhD or Post-doctoral research project with a specialism in Organic Synthesis or Process Chemistry.

    · Demonstrated expertise in early, mid or late-phase route and process development for the manufacture of APIs, intermediates and raw materials, and/or experience with quality by design, technology transfer and commercial production would also be advantageous.

    · The candidate is expected to conduct practical, laboratory-based chemistry projects to develop routes and processes and then scale-up to manufacture

    · Higher or bachelor's degree in chemistry or related scientific discipline with relevant experience in a chemistry laboratory environment.

    · In-depth, hands-on expertise and up-to-date knowledge of a wide range of organic chemistry transformations.

    · Strong scientific track record.

    Key Roles and Responsibilities

    · Design and conduct laboratory experimentation to deliver customer projects.

    · Deliver new routes and processes for early-phase APIs and intermediates to enable scale-up to 35 L at Alderley Park.

    · Deliver optimised processes for mid and late-phase APIs and intermediates to enable scale-up to pilot and production facilities in India.

    · Working within multi-functional project teams operating to tight deadlines.

    · Maintain an organised and safe lab environment and encourage others to achieve the same.

    · Contribute to project definition activities (proposal writing etc) and support business development activities as required.

    Key Attributes

    · Learning agility in the utilisation of new technologies and approaches to support chemistry projects.

    · Ability to solve complex scientific problems.

    · Excellent communication; both verbal and written.

    o This includes the ability to accurately detail laboratory experimentation in an electronic notebook and ability to write clear and concise project reports and slides as required.

    · A team player.

    · Conscientious with a can-do attitude with good attention to detail.

    The Offer

    · A competitive Salary and Benefits package including company pension, health and life insurance, minimum of 25 days holiday per year and enhanced family leave.

    · Work in a state-of-the-art facility on one of the country's leading Biotech & Life Science Parks.

    · Flexible working hours and conditions to suit the right candidate.

    As an Equal Opportunities employer, we welcome applications from all suitably qualified persons regardless of their race, sex, disability, religion/belief, sexual orientation or age.

    Please note that Sai Life Sciences Ltd is unable to sponsor the visas for any candidates for the above role.

    Process Development Chemist (all levels)

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