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Technical Content Developer
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Technical Lead Developer Up to
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eFinancialCareers London, United Kingdom**About the Team** · Citi is a leading global financial services company having 200 million customer accounts. Citi does business in more than 100 countries, providing consumers, corporations, governments and institutions with a broad range of financial products and services, inc ...
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Recruitment Genius London, United KingdomAs a current technical NPD manager, how much do you enjoy reacting to external stimulus, but also bringing your own ideas and creativity to New Product Development? If the answer is "not enough" we'd be happy to hear from you about our remote based role. · What will your key resp ...
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Technical Lead Developer
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Technical Developer Lead
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Development and Technical Coordinator
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Development and Technical Coordinator
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Technical Developer Lead
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Development and Technical Coordinator
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Development and Technical Coordinator
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Development and Technical Coordinator
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Technical Analyst Developer
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Development and Technical Coordinator
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Development and Technical Coordinator
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Kenna Recruitment Ltd London, United KingdomUp to £43k + PackageMy client is one of the UK's largest Housing Associations currently looking for an Assistant Technical Coordinator to join their team in Central London. This is an excellent opportunity to join a charitable organisation that goes beyond providing homes and hou ...
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Technical Lead Developer
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Technical and Development Manager
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EPC-UK, Ltd. United KingdomEPC Metrics' latest developments — with Technical Director, Dr. His accomplishments include the development of EPC-UK's seismograph technology, together with research into advancing the use of high-speed cameras to improve blast optimisation and 'planning to comply' models. He ha ...
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Development and Technical Coordinator
1 day ago
O'Neill & Brennan UK United KingdomThe scheme will consist of over 3,000 units in addition to retail and commercial space, and is due to be ongoing for circa 20 more years. This role will include working with the site management team and coordinating the mechanical and electrical elements of the project. You will ...
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Development and Technical Coordinator
1 day ago
D R Newitt Recruitment England, United KingdomJob Description · Job Title: Technical Coordinator · Location: Kent · Salary: Up to £34,000 · Hours: Monday to Friday · Responsibilities · Assisting the Technical Manager with all tasks within the day-to-day running of the Technical Department. · Management of product speci ...
Scientist, Cell and Gene Technical Development - London, United Kingdom - Orchard Therapeutics
Description
Location:
London, UKReporting to: Principal Scientist, Cell and Gene Technical Development
Job Summary:
This is an exciting opportunity for a well-qualified candidate to join an international company focused on transforming the lives of patients with rare disorders through innovative gene therapies.
Orchard Therapeutics, Ltd.(OTL) is looking for a Scientist I or II (depending on experience) for the Process Development team, focused on the development of analytical assays for Orchard Therapeutics innovative gene-modified cell-based therapeutic products.
Primary activities will include developing, validating and performing analytical assays for process development, QC and characterization of lentiviral vector and HSC gene therapy products.
The post may also include research with internal departments and external partners, including development, validation and technology transfer, to support OTL's product pipeline programs.
The role will be based in Orchard's London Hammersmith site where the state-of-the-art development laboratories are located.Key Elements And Responsibilities Develop, validate and perform analytical assays for process development, implementation as QC and/or characterization assays for lentiviral vector and HSC gene therapy products Involvement in the transfer of processes and analytical methods from external collaborators and internal Orchard Research team to the Technical Development team.
Assessment of novel equipment and methodologies for lentiviral vector and HSC DP analytics.Participate in the Technical Development team through generation and testing of lentiviral vectors, and involvement in the optimization and improving lentiviral vector and HSC manufacturing processes.
Assist in lab management duties, stock management and equipment maintenance and other practical day-to-day activities in the lab.Keep accurate and contemporaneous records of all development activities and analysis in Orchard's electronic lab notebook, presentations and/or reports, and present to the wider team/department.
Authoring, reviewing and editing batch records, SOPs, development protocols and reports for internal and external analytical development, and CMC regulatory submissions.
As required, manage activities at CDMOs and CTOs for the tech transfer, development, and validation of analytical methods, including the design, review and approval of associated protocols, test records/forms, reports and SOPs.
Other activities may be assigned as required, in agreement with line management.RequirementsRequired KnowledgeAs a Proven Technical Expert In The Development, Manufacture And Delivery Of Cell-based Therapy Products With Significant Applied Experience In The Biotechnology Industry, This Candidate Will Possess Experience in the biotechnology or pharma industry (including PhD or industry/academic work where relevant), with the ability to design, validate and apply analytical methods for cell and gene therapy product development, characterization and QC testing.
Capable of independently designing experiments to develop analytical methods and, with support, validation and tech transfer as required.Hands-on experience of the development, validation and application of analytical techniques such as FACS, ddPCR, ELISA, DNA sequencing, qPCR/PCR, cell culture and cell-based assays.
Knowledge of European and US Pharmacopeia methods and FDA, EMA, GMP, WHO and ICH regulatory requirements if preferred. Sound understanding and demonstrated application of statistical methods/tools would be advantageous.Skills And Abilities Excellent written and oral communication skills Excellent interpersonal skills Outstanding organizational skills Creative problem solver Ability to operate in a fast-paced, multi-disciplinary industrial environment Proven ability to work effectively in multi-site, cross-functional working environment.
Education BSc/MSc with relevant industry experience, or PhD in biotechnology/biological sciences, gene therapy, analytical development or an associated discipline.
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