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    Biologist - United Kingdom - Ochre Bio

    Ochre Bio
    Ochre Bio United Kingdom

    3 days ago

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    Description

    Summary We are looking for a talented and highly motivated Principal Computational Biologist to join Ochre Bio's In Silico Biology team on an exciting journey to support the development of advanced RNA medicines for one of the most pressing healthcare challenges of our time.

    This role will be based at Oxford Science Park. UK remote work is possible, with site visits.

    Lead the 'advanced modelling' squad within the In Silico Biology Team, and be the point of contact and a role model for advanced modelling within the company.

    Maintain strong domain knowledge of leading 'omics' and 'big data' computational methods
    Drive experimental design & modelling of deep phenotyping and/ or omics data in close collaboration with wet-lab scientists. Work as a member of cross-functional teams bringing together best-in-class Drug Discovery, Drug Development, Product & Project Management capabilities.
    Routinely use Python/R for data analyses, in particular data wrangling, modelling and visualisation. Develop solutions to increase automation, reliability and scalability of our data processing pipelines and workflows.
    Maintain progress in personal and professional development to better domain, technical, and professional skills.
    Present research updates to project teams and to the management team.
    Contribute to training initiatives to foster a data-driven culture.

    PhD in computational biology or related
    Experience in delivering results in a fast-paced environment (biotech / pharma industries would be a distinct advantage)
    Strong experience with experimental design, exploratory data analysis, reporting and visualisation of data.
    Experience in leading projects involving multiple stakeholders, end-to-end.

    Experience with pipelines / reproducible scientific workflows development (i.e. Deep understanding of human biology beyond the statistical/ML models being developed
    Good knowledge with rapidly prototyping, writing and maintaining Python and/or R code, harnessing statistical tools for biological interpretations.
    Familiarity with project management tools (SmartSheet / JIRA/ ClickUp)
    Familiarity with cloud computing (AWS)


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