- Ensure the safety and welfare of trial participants and the delivery of high-quality studies in the Clinical Pharmacology Unit, in accordance with Simbec-Orion's Quality Management System, ICH-GCP; MHRA Phase I accreditation requirements and The Independent Health Care (Wales) Regulations 2011 at all times.
- Assess and develop key trial documents and reports (including study protocols, Risk Management Plans, study-specific training and safety reports) and advise/present on project safety, feasibility, and operationalisation internally and with clients.
- Perform screening, ongoing monitoring and post-study clinical examinations (including review of ECGs, vital signs, Spirometry, Holter, Laboratory results and management and assessment of adverse events) and clinical procedures as appropriate to each study (cannulation, dosing procedures, nasogastric tubes, skin biopsy samples etc.); reporting any clinically significant abnormal results and/or changes from baseline and action taken to the designated Study Principal Investigator, Senior Medical Director and/or Sponsors.
- Evaluate participant's eligibility and obtain written informed consent for inclusion in a specific study according to the information in the Investigator Brochure, Protocol and Informed Consent Document.
• Supports effective communication with volunteers' General Practitioners regarding their participation in a study, collaborative care and follow-up. - Act as a Principal Investigator (including First in Human) / Sub-Investigator for clinical trials to the highest standards, including actively participating in data review and taking responsibility for trial (including dose escalation) decisions, and liaison with hospital specialists, GPs, consultants and others to recruit suitable volunteers and patients for clinical trials.
- Be proficient in Advanced Life Support and capable of dealing with acute medical emergencies that may arise in the Clinic Pharmacy Unit. Provide medical cover outside of normal working hours as part of an On-Call Rota.
- Line Management of Research Physicians and provide leadership support and guidance to the Heads of Departments for the Clinic and Enrolment Services departments to fulfil their roles successfully; Deputise for the Senior Medical Director.
- Participate in Commercial Development activities (including Feasibility assessment and Budget reviews when required) and take an active role in providing feasibility and strategic advice for proposal development at key client meetings and Bid Defence Meetings; Represent Simbec-Orion at national and international meetings/conferences seminars and workshops.
- Collaborate and consult with others to develop and maintain strong working relationships with peers, senior leaders, and key stakeholders to ensure projects are delivered on schedule and within budget.
- Medical Degree with GMC Registered with a License to Practice and comply with revalidation requirements
- Post-graduate Qualification in Clinical Pharmacology/Pharmaceutical Medicine (eligible to be First-in-Human Principal Investigator)
- Experience in the conduct of Clinical Trials in a Clinical Pharmacology Unit
- Experience as Principal Investigator of FiH studies, including significant experience in the interpretation of non-clinical data
- Thorough understanding of MHRA Phase I Accreditation requirements
- Excellent verbal and written skills, with the ability to tailor communication to various stakeholders
- Experience managing participant safety (eligibility, ongoing review/assessment) and managing Medical Emergencies
- Competent in MS Office Packages
- Understanding and meeting the needs of clients and the business
- Strong leadership, line management and teamwork skills
- Valid Advanced Life Support (ALS) certificate from the Resuscitation Council (UK)
- Previous Bio-Tech /Pharma Experience
- Experience in leading cross-functional project/clinical teams
- Competent in using Electronic Data Capturing Systems
- Experience in business development activities, including feasibility and strategic advice for proposal development and bid-defence meetings
- Experience with Clinical Trial Management Systems (CTMS)
-
Associate Medical Director
3 days ago
Simbec-Orion Merthyr Tydfil, United KingdomABOUT US: · Simbec-Orion is a responsive and agile full-service CRO, with wide therapeutic experience and specialist expertise in clinical pharmacology, oncology and rare diseases. Perfectly structured, we provide full-service clinical development solutions for small and mid-size ...
-
Medical Director
22 hours ago
Welsh Blood Service Pontyclun, United KingdomThe Welsh Blood Service (WBS) is immensely proud of the vital role it plays in modern healthcare, striving to save and transform lives through the generosity of donors. We provide an essential service for NHS Wales in ensuring that it has access to blood to support the treatment ...
-
Medical Director
1 day ago
Welsh Blood Service Pontyclun, United KingdomThe Welsh Blood Service (WBS) is immensely proud of the vital role it plays in modern healthcare, striving to save and transform lives through the generosity of donors. We provide an essential service for NHS Wales in ensuring that it has access to blood to support the treatment ...
-
Associate Medical Director
5 days ago
Simbec-Orion Merthyr Tydfil (Merthyr Tudful), United Kingdom Full timeABOUT US · Simbec-Orion is a responsive and agile full-service CRO, with wide therapeutic experience and specialist expertise in clinical pharmacology, oncology and rare diseases. Perfectly structured, we provide full-service clinical development solutions for small and mid-size ...
-
Associate Medical Director Mental Health
5 days ago
Cwm Taf Morgannwg University Health Board Pontypridd, United KingdomWelsh Health Specialised Services Committee which works on behalf the 7 Health Boards in Wales to commission specialised and highly specialised services are now looking to recruit an Associate Medical Director in Mental Health. · This post offers the opportunity to work at a seni ...
-
Associate Medical Director Mental Health
6 days ago
Cwm Taf Morgannwg University Health Board Pontypridd, United KingdomWelsh Health Specialised Services Committee which works on behalf the 7 Health Boards in Wales to commission specialised and highly specialised services are now looking to recruit an Associate Medical Director in Mental Health. · This post offers the opportunity to work at a seni ...
-
Assistant Medical Director: Quality, Safety
6 days ago
Powys Teaching Health Board Bronllys, United KingdomWe are looking to recruit an exceptional Assistant Medical Director: Quality and Safety and Clinical Governance who has a proven track record of successfully delivering a complex portfolio. ...
-
Locum Consultant Paediatrician
1 day ago
Cwm Taf Morgannwg University Health Board Merthyr Tydfil, United KingdomTHIS POST IS FIXED TERM FOR UP TO 6 MONTHS DUE TO MEET THE NEEDS OF THE SERVICE · This is a locum post to cover sickness. There is retirement vacancy to follow, therefore there is a potential for a substantive role following the recruitment procedures. This is a traditional consu ...
-
Senior Director, Medical Writing
5 days ago
Bryn Mawr College Brynmawr, Blaenau Gwent, United KingdomOur dedicated and passionate AmeriCorps members work closely with students, providing individualized attention that helps them feel valued and supported in their learning. In addition to 1:1 tutoring, CYP AmeriCorps members mentor students in small groups, organize school-wide ev ...
-
Deputy Regional Medical Director
1 week ago
Cygnet Health Care Wales, United KingdomAre you an outstanding Medical Director looking for new challenge, career development and a competitive salary? · We are looking for a Deputy Regional Medical Director and Consultant Psychiatrist to support our services in the Northwest and Wales. · Please be aware that the ba ...
-
Deputy Regional Medical Director
1 week ago
Cygnet Health Care Wales, United KingdomAre you an outstanding Medical Director looking for new challenge, career development and a competitive salary? · We are looking for a Deputy Regional Medical Director and Consultant Psychiatrist to support our services in the Northwest and Wales. · The Deputy Regional Medical D ...
-
Deputy Group Medical Director
6 days ago
Swansea Bay University Health Board Port Talbot, United KingdomJob Details · Applications are invited for a newly developed (job share) post of Deputy Group Medical Director of Primary Care. This opportunity will be made up of two positions with a shared commitment of 8 sessions per week and will be offered for a 12 month period as a fixed ...
-
Head of Quality Assurance
6 days ago
Cwm Taf Morgannwg University Health Board Abercynon, United KingdomAn exciting opportunity has arisen for a Head of Quality Assurance & Compliance. You will be responsible for providing professional leadership and management of the quality assurance, compliance and regulatory functions. You will possess excellent interpersonal and communication ...
-
Support Medical Secretary
1 week ago
Cwm Taf Morgannwg University Health Board Pontypridd, United KingdomAs Support Secretary the postholder will be required to provide a range of secretarial and clerical services to support the smooth running of day to day operational issues for the supporting the Clinical Teams, thus enabling a whole team approach with the aim of improving patient ...
-
Support Medical Secretary
1 week ago
Cwm Taf Morgannwg University Health Board Pontypridd, United KingdomAs Support Secretary the post holder will be required to provide a range of secretarial and clerical services to support the smooth running of day to day operational issues for Clinical Teams, thus enabling a whole team approach with the aim of improving patient services and care ...
-
Team Secretary
3 days ago
Cwm Taf Morgannwg University Health Board Pontypridd, United KingdomAs Team Secretary the post-holder will be required to provide a range of secretarial and clerical services to support the smooth running of day to day operational issues for the Consultant Psychiatrist and Community Mental Health Team, thus enabling a whole team approach with the ...
-
Aneurin Bevan University Health Board Newbridge, United KingdomThe post holder will be responsible for providing senior management in partnership to ensure the delivery of innovative patient focused pathways across the HB, which optimise the delivery of services to meet the needs of individual patients and national and local priorities and s ...
-
Rsu Administrator
22 hours ago
Health Education and Improvement Wales Nantgarw, United KingdomThe Revalidation Support Unit is a professional unit within Health Education and Improvement Wales (HEIW) that aims to support and improve professional standards across Wales. The Unit has responsibility for: · - Management of the GP Appraisal Process for all GPs in Wales on beha ...
-
Rsu Administrator
6 days ago
Health Education and Improvement Wales Nantgarw, United KingdomRevalidation Support Unit (RSU) · The Revalidation Support Unit is a professional unit within Health Education and Improvement Wales (HEIW) that aims to support and improve professional standards across Wales. The Unit has responsibility for: · - Management of the GP Appraisal Pr ...
-
Consultant in Camhs
6 days ago
Cwm Taf Morgannwg University Health Board Bridgend, United KingdomThe post holder is ultimately accountable to the medical director but works closely with support and supervision form the Community Paediatric Lead for CYP ( Assistant Clinical Director CYP) Will be expected to comply with the health Boards agreed policies and procedures and to p ...
Associate Medical Director - Merthyr Tydfil, Wales, United Kingdom - Simbec-Orion
Description
ABOUT US
Simbec-Orion is a responsive and agile full-service CRO, with wide therapeutic experience and specialist expertise in clinical pharmacology, oncology and rare diseases. Perfectly structured, we provide full-service clinical development solutions for small and mid-size drug developers - headed up by a centralised leadership team. With a focus on tailormade and scalable solutions, we'll adapt our delivery style, communications and operations to suit the demands of the project, helping clients achieve their clinical and commercial objectives. Because our goal is the same as theirs; to improve patients' lives.THE ROLE We are looking for an Associate Medical Director to join our Medical-Clinical Pharmacology team. You will be responsible for ensuring that all projects are designed, executed, and delivered safely to meet clients' development needs while ensuring the safety and welfare of trial participants and data integrity within the Clinical Pharmacology Unit at all times. You will ensure that all procedures are performed to acceptable Medical, Scientific and Ethical Standards and that all trials are run in accordance with protocols and standard operating procedures (SOPs) and meet all regulatory requirements and ICH-GCP. Responsible for the line management of the Research Physician team, sharing their knowledge and supporting the team's competency. You will also act as Principal Investigator on studies including First-in-Human Trials.
KEY ACCOUNTABILITIES
#J-18808-Ljbffr